Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.74 |
| ▸ | DHODH | Q02127 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 2/20 | 0.54 |
| ▸ | MAOB | P27338 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | TOP1 | P11387 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | ACP1 | P24666 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26997351 | 0.91 | DHODH (0.58) | CYP19A1DHODHMAOAMAOBNPC1 | |
| SCHEMBL26997370 | 0.79 | DHODH (0.47) | CYP19A1DHODHMAOAMAOBNPC1 | |
| SCHEMBL29398665 | 0.79 | MAOA (0.49) | CYP19A1DHODHMAOAMAOBNPC1 | |
| SCHEMBL22191688 | 0.79 | MAOA (0.49) | CYP19A1DHODHMAOAMAOBNPC1 | |
| SCHEMBL25425228 | 0.79 | MAOA (0.49) | CYP19A1DHODHMAOAMAOBNPC1 | |
| SCHEMBL26998020 | 0.77 | MAOA (0.50) | CYP19A1DHODHMAOAMAOBNPC1 | |
| SCHEMBL26997345 | 0.75 | NCF1 (0.52) | CYP19A1DHODHMAPTHTTMAPK1 | |
| SCHEMBL12402661 | 0.74 | CYP19A1 (0.80) | CYP19A1DHODHTOP1KDM4EL3MBTL1 | |
| SCHEMBL8657096 | 0.73 | TOP1 (0.63) | CYP19A1DHODHTOP1KDM4EL3MBTL1 | |
| SCHEMBL8587249 | 0.72 | IDO1 (0.45) | CYP19A1DHODHKDM4EMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060128702-A1 | Heterocyclic and bicyclic compounds, compositions and methods | REDDY US THERAPEUTICS, INC. | 2006-06-15 | — | — | US | claimed |
| WO-2006058201-A2 | HETEROCYCLIC AND BICYCLIC COMPOUNDS, COMPOSITIONS AND METHODS | REDDY US THERAPEUTICS, INC. (US) | 2006-06-01 | — | — | WO | claimed |
| US-20060128702-A1 | Heterocyclic and bicyclic compounds, compositions and methods | REDDY US THERAPEUTICS, INC. | 2006-06-15 | — | — | US | disclosed |
| WO-2006058201-A2 | HETEROCYCLIC AND BICYCLIC COMPOUNDS, COMPOSITIONS AND METHODS | REDDY US THERAPEUTICS, INC. (US) | 2006-06-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060128702-A1 | Heterocyclic and bicyclic compounds, compositions and methods | HPSE, ENGASE, UGCG | CYP19A1 863/4885DHODH 855/4885MAOA 1504/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.