Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | PDE5A | O76074 | 5/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.45 |
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 8/20 | 0.42 |
| ▸ | LMNA | P02545 | 8/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 7/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | USP2 | O75604 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 5/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26997345 | 0.78 | NCF1 (0.52) | IDO1PDE5APTGS1TBXAS1PTGS2 | |
| SCHEMBL26997351 | 0.77 | DHODH (0.58) | PDE5APTGS1TBXAS1PTGS2PDE3B | |
| SCHEMBL27560291 | 0.75 | DHODH (0.44) | IDO1PDE5APTGS1TBXAS1PTGS2 | |
| SCHEMBL26997372 | 0.75 | CYP3A4 (0.51) | IDO1PDE5APTGS1TBXAS1PTGS2 | |
| SCHEMBL26997362 | 0.73 | KDM4E (0.55) | CYP3A4CYP1A2LMNACYP2D6CYP2C19 | |
| SCHEMBL4278249 | 0.73 | KDM4E (0.49) | CYP1A2LMNACYP2C19MEN1KMT2A | |
| SCHEMBL8436958 | 0.72 | IDO1 (0.61) | IDO1CYP11B1CYP11B2CYP3A4CYP1A2 | |
| SCHEMBL26997358 | 0.72 | KDM4E (0.56) | PDE5ACYP3A4CYP1A2LMNACYP2D6 | |
| SCHEMBL5800340 | 0.72 | CYP19A1 (0.74) | DHODHCYP11B1CYP11B2CYP3A4CYP1A2 | |
| SCHEMBL26998341 | 0.71 | CGAS (0.51) | IDO1PDE5APTGS1TBXAS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0876345-A1 | HETEROCYCLIC COMPOUNDS AS H+-ATPASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-11-11 | — | — | EP | disclosed |
| WO-1997014681-A1 | HETEROCYCLIC COMPOUNDS AS H+-ATPASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-04-24 | — | — | WO | disclosed |