Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5559520 | 0.93 | TRPV1 (0.37) | TRPV1POLBCNR1CNR2CYP2B6 | |
| SCHEMBL5559519 | 0.93 | TRPV1 (0.37) | TRPV1POLBCNR1CNR2CYP2B6 | |
| SCHEMBL5558889 | 0.91 | CCKBR (0.38) | TRPV1POLB | |
| SCHEMBL5558899 | 0.91 | CCKBR (0.38) | TRPV1POLB | |
| SCHEMBL5559003 | 0.90 | EGLN1 (0.37) | PTGS2TRPV1PTGS1POLBCNR1 | |
| SCHEMBL5559007 | 0.90 | EGLN1 (0.37) | PTGS2TRPV1PTGS1POLBCNR1 | |
| SCHEMBL5559001 | 0.90 | EGLN1 (0.37) | PTGS2TRPV1PTGS1POLBCNR1 | |
| SCHEMBL5800286 | 0.90 | TRPV1 (0.36) | PTGS2TRPV1PTGS1POLBCXCL8 | |
| SCHEMBL5800356 | 0.89 | PTGS2 (0.44) | PTGS2PTGS1 | |
| SCHEMBL5560445 | 0.88 | POLB (0.37) | PTGS2TRPV1POLBCNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006050120-A2 | SYNTHESIS OF COX-2 AND FAAH INHIBITORS | MICROBIA, INC. (US) | 2006-05-11 | — | — | WO | disclosed |