Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALPG | P10696 | 1/20 | 0.53 |
| ▸ | S100A4 | P26447 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | CDK2 | P24941 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | PIM1 | P11309 | 2/20 | 0.41 |
| ▸ | AURKA | O14965 | 2/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.41 |
| ▸ | PRKCG | P05129 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21801897 | 0.71 | S100A4 (0.56) | MAPTRAB9AMEN1KMT2ATDP1 | |
| SCHEMBL3759875 | 0.71 | MAPT (1.00) | MAPTRAB9AMEN1KMT2ATDP1 | |
| SCHEMBL4433324 | 0.67 | GRM5 (0.54) | MAPTRAB9AMEN1KMT2ATDP1 | |
| SCHEMBL2599222 | 0.65 | S100A4 (1.00) | RAB9AMEN1KMT2AS100A4MAPK1 | |
| SCHEMBL11358184 | 0.65 | S100A4 (0.59) | MAPTMEN1KMT2AKDM4ES100A4 | |
| SCHEMBL28289103 | 0.65 | S100A4 (0.59) | MAPTMEN1KMT2AKDM4ES100A4 | |
| SCHEMBL21312575 | 0.65 | MEN1 (0.49) | MAPTRAB9AMEN1KMT2ATDP1 | |
| Diphenylamine SCHEMBL9632812 | 0.65 | HSD17B10 (0.67) | MAPTRAB9AMEN1KMT2ATDP1 | |
| SCHEMBL2113287 | 0.65 | MAPT (0.55) | MAPTRAB9AMEN1KMT2ATDP1 | |
| SCHEMBL14308717 | 0.64 | CDK2 (0.74) | MAPTRAB9AMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006081327-A2 | SMALL MOLECULES THAT REDUCE FUNGAL GROWTH | UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE (US) | 2006-08-03 | — | — | WO | disclosed |
| EP-0107367-B1 | 6-SUBSTITUTED-QUINOLINE-5,8-QUINONES | ELI LILLY AND COMPANY (US) | 1989-08-02 | — | — | EP | disclosed |
| US-4492704-A | ANTHISTAMINES | ELI LILLY AND COMPANY (US) | 1985-01-08 | — | — | US | disclosed |
| EP-0107367-A2 | 6-Substituted-quinoline-5,8-quinones | ELI LILLY AND COMPANY (US) | 1984-05-02 | — | — | EP | disclosed |