Diphenylamine

Diphenylamine

SCHEMBL9632812

O=C1C=CC(=O)C=C1.c1ccc(Nc2ccccc2)cc1

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 6/20 0.67
ALDH1A1 P00352 8/20 0.63
TDP1 Q9NUW8 6/20 0.63
ALOX12 P18054 4/20 0.63
L3MBTL1 Q9Y468 4/20 0.63
TSHR P16473 4/20 0.63
MAPK1 P28482 4/20 0.63
ALOX15 P16050 2/20 0.63
PTGS1 P23219 1/20 0.63
SLC6A2 P23975 1/20 0.63
PTGS2 P35354 1/20 0.63
HTR2B P41595 1/20 0.63
MAPT P10636 7/20 0.55
MEN1 O00255 4/20 0.55
KMT2A Q03164 4/20 0.55
AR P10275 1/20 0.55
HSP90AA1 P07900 1/20 0.54
CYP3A4 P08684 6/20 0.50
HPGD P15428 4/20 0.50
HTT P42858 3/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diphenylamine SCHEMBL6828443 0.82 HSD17B10 (1.00) HSD17B10ALDH1A1TDP1ALOX12L3MBTL1
Diphenylamine SCHEMBL3003404 0.82 HSD17B10 (1.00) HSD17B10ALDH1A1TDP1ALOX12L3MBTL1
Diphenylamine SCHEMBL1619083 0.82 HSD17B10 (1.00) HSD17B10ALDH1A1TDP1ALOX12L3MBTL1
Diphenylamine SCHEMBL301493 0.82 HSD17B10 (1.00) HSD17B10ALDH1A1TDP1ALOX12L3MBTL1
Diphenylamine SCHEMBL229 0.82 HSD17B10 (1.00) HSD17B10ALDH1A1TDP1ALOX12L3MBTL1
SCHEMBL11689083 0.80 ALDH1A1 (0.53) HSD17B10ALDH1A1TDP1ALOX12L3MBTL1
Diphenylamine SCHEMBL8920423 0.79 HSD17B10 (0.80) HSD17B10ALDH1A1TDP1ALOX12L3MBTL1
Diphenylamine SCHEMBL23295988 0.78 HSD17B10 (0.92) HSD17B10ALDH1A1TDP1ALOX12L3MBTL1
Diphenylamine SCHEMBL634477 0.78 HSD17B10 (0.92) HSD17B10ALDH1A1TDP1ALOX12L3MBTL1
Diphenylamine SCHEMBL2235057 0.78 HSD17B10 (0.92) HSD17B10ALDH1A1TDP1ALOX12L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5130471-A Storage stability of acrylic monomers by addition of cyclic amine and phenothiazine NALCO COMPANY 1992-07-14 US disclosed
US-4021310-A Method for inhibiting the polymerization of acrylic acid or its esters NIPPON SHOKUBAI KAGAKU KOGYO CO., LTD. (JA) 1977-05-03 US disclosed