Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SLC10A6 | Q3KNW5 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27868477 | 0.80 | MAPT (0.44) | ALDH1A1KMT2AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL3673340 | 0.78 | MAPT (0.53) | ALDH1A1KMT2AMEN1SMN1; SMN2MAPK10 | |
| SCHEMBL4307844 | 0.78 | MAPT (0.42) | ALDH1A1KMT2AMEN1SMN1; SMN2KDM4E | |
| SCHEMBL5454754 | 0.76 | SLC6A3 (0.50) | ALDH1A1KMT2AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL16212756 | 0.75 | PDGFRB (0.40) | ALDH1A1KMT2AMEN1SMN1; SMN2KDM4E | |
| SCHEMBL23412561 | 0.73 | GAA (0.39) | ALDH1A1KMT2ASMN1; SMN2KDM4ESIRT6 | |
| SCHEMBL1527614 | 0.73 | CHEK1 (0.37) | ALDH1A1KMT2AMEN1SMN1; SMN2SIRT6 | |
| SCHEMBL22128104 | 0.72 | POLB (0.39) | ALDH1A1KMT2AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL1848834 | 0.72 | ALDH1A1 (0.60) | ALDH1A1KMT2ASMN1; SMN2KDM4EMAPK10 | |
| SCHEMBL5949858 | 0.72 | SLC6A4 (0.54) | ALDH1A1KMT2AMEN1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006065788-A2 | NOVEL MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2006-06-22 | — | — | WO | disclosed |