Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 5/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.33 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5784218 | 0.85 | MAPT (0.53) | CYP1A2CYP2A6MAPTHTTSMN1; SMN2 | |
| SCHEMBL1295362 | 0.77 | MAPT (0.35) | MAPTHTTKDM4EHSP90AA1HSD17B10 | |
| SCHEMBL19121786 | 0.77 | CYP2A6 (0.50) | CYP1A2CYP2A6MAPTHTTSMN1; SMN2 | |
| SCHEMBL5993713 | 0.76 | CYP1A2 (0.44) | CYP1A2CYP2A6MAPTHTTSMN1; SMN2 | |
| SCHEMBL12706607 | 0.76 | CYP1A2 (0.47) | CYP1A2CYP2A6MAPTHTTALDH1A1 | |
| SCHEMBL1261956 | 0.75 | ALDH1A1 (0.48) | MAPTHTTALDH1A1KDM4EHSP90AA1 | |
| SCHEMBL1747611 | 0.75 | MAPT (0.46) | MAPTHTTALDH1A1KDM4EPOLB | |
| SCHEMBL30873742 | 0.75 | MAPT (0.46) | MAPTHTTALDH1A1KDM4EPOLB | |
| SCHEMBL13219654 | 0.75 | CYP1A2 (0.48) | CYP1A2CYP2A6MAPTHTTSMN1; SMN2 | |
| SCHEMBL12751165 | 0.75 | MAPT (0.34) | MAPTHTTKDM4EHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025227032-A1 | METHODS FOR DEGRADATION OF CYCLIN K AND INHIBITION OF CYCLIN DEPENDENT KINASES | REMIX THERAPEUTICS INC. (US) | 2025-10-30 | — | — | WO | disclosed |
| CN-117384154-A | Pyrroloquinolinone compound, synthesis method and application thereof | 广州医科大学 | 2024-01-12 | — | — | CN | disclosed |
| US-20230128402-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | THE TRUSTEES OF PRINCETON UNIVERSITY | 2023-04-27 | — | — | US | disclosed |
| EP-4093400-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | The Trustees of Princeton University (US) | 2022-11-30 | — | — | EP | disclosed |
| WO-2021151062-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | THE TRUSTEES OF PRINCETON UNIVERISTY (US) | 2021-07-29 | — | — | WO | disclosed |
| US-7491722-B2 | Pyridazin-3(2H)-one derivatives | LABORATORIOS ALMIRALL S.A. (ES) | 2009-02-17 | — | — | US | disclosed |
| US-20060111369-A1 | Synthesis, characterization and biological action of optically active isomers of floxacins | SOMBERG JOHN C | 2006-05-25 | — | — | US | disclosed |
| WO-2006052264-A2 | SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL ACTION OF OPTICALLY ACTIVE ISOMERS OF FLOXACINS | SOMBERG JOHN CHARIN (US) | 2006-05-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060111369-A1 | Synthesis, characterization and biological action of optically active isomers of floxacins | TNNI3, TNNC1, TNNT2 | CYP1A2 3237/4885CYP2A6 1470/4885MAPT 4751/4885 |
| US-20230128402-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | PAH, ALDH2, IDH2 | CYP1A2 329/4885CYP2A6 1025/4885MAPT 4685/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.