Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL468372 | 0.86 | ALDH1A1 (0.61) | MAPTKDM4EALDH1A1MAPK1MEN1 | |
| SCHEMBL17038122 | 0.85 | MAPT (0.56) | MAPTKDM4EALDH1A1MAPK1KMT2A | |
| SCHEMBL28504439 | 0.82 | MAPT (0.53) | MAPTKDM4EALDH1A1MAPK1MEN1 | |
| SCHEMBL2421954 | 0.82 | MAPT (0.60) | MAPTKDM4EALDH1A1MAPK1MEN1 | |
| SCHEMBL10932609 | 0.82 | MAPT (0.63) | MAPTKDM4EALDH1A1MAPK1MEN1 | |
| SCHEMBL8107611 | 0.80 | MAPT (0.60) | MAPTKDM4EALDH1A1MAPK1MEN1 | |
| SCHEMBL24993978 | 0.80 | KAT2B (0.63) | MAPTALDH1A1KMT2ALMNAPRSS1 | |
| SCHEMBL29557476 | 0.80 | ALDH1A1 (0.51) | MAPTKDM4EALDH1A1MAPK1MEN1 | |
| SCHEMBL1086052 | 0.80 | KMT2A (0.58) | MAPTKDM4EALDH1A1MAPK1MEN1 | |
| SCHEMBL10941513 | 0.80 | MAPT (0.57) | MAPTALDH1A1MAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006067406-A1 | IMMUNOMODULATORY PEPTIDE FRAGMENTS OF CD23 AND USES THEREFOR | ISIS INNOVATION LIMITED (GB) | 2006-06-29 | — | — | WO | disclosed |