Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 9/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6159827 | 0.89 | ALDH1A1 (0.51) | ALDH1A1MAPTKDM4EPKMMAPK1 | |
| SCHEMBL29359698 | 0.89 | ALDH1A1 (0.51) | ALDH1A1MAPTKDM4EPKMMAPK1 | |
| SCHEMBL6671231 | 0.89 | ALDH1A1 (0.51) | ALDH1A1MAPTKDM4EPKMMAPK1 | |
| SCHEMBL21981238 | 0.84 | ALDH1A1 (0.57) | ALDH1A1MAPTKDM4EPKMMAPK1 | |
| SCHEMBL29411662 | 0.84 | ALDH1A1 (0.57) | ALDH1A1MAPTKDM4EPKMMAPK1 | |
| SCHEMBL27501764 | 0.81 | ALDH1A1 (0.53) | ALDH1A1MAPTKDM4EPKMMAPK1 | |
| SCHEMBL21981237 | 0.81 | ALDH1A1 (0.49) | ALDH1A1MAPTKDM4EMAPK1MEN1 | |
| SCHEMBL5800525 | 0.80 | MAPT (0.53) | ALDH1A1MAPTKDM4EPKMMAPK1 | |
| SCHEMBL8375662 | 0.80 | MAPT (0.48) | ALDH1A1MAPTKDM4EPKMMAPK1 | |
| SCHEMBL14255280 | 0.79 | ALDH1A1 (0.55) | ALDH1A1MAPTKDM4EPKMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4058448-B1 | HYDANTOIN DERIVATIVES AS ADAMTS7 ANTAGONISTS FOR THE TREATMENT OF CARDIOVASCULAR DISEASES | BAYER AG (DE) | 2024-05-29 | — | — | EP | disclosed |
| EP-3765022-B1 | PYRIDIN-2-YL ALKYLAMINO SUBSTITUTED HYDROXAMIC ACID AND USES THEREOF | HAWAII BIOTECH INC (US) | 2024-05-01 | — | — | EP | disclosed |
| US-20230027985-A1 | SUBSTITUTED HYDANTOINAMIDES AS ADAMTS7 ANTAGONISTS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-01-26 | — | — | US | disclosed |
| US-11306302-B2 | Soluble Sortase A | HOFFMANN-LA ROCHE INC. (US) | 2022-04-19 | — | — | US | disclosed |
| US-11299461-B2 | Pyridin-2-yl alkylamino substituted hydroxamic acid and uses thereof | HAWAII BIOTECH, INC. (US) | 2022-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230027985-A1 | SUBSTITUTED HYDANTOINAMIDES AS ADAMTS7 ANTAGONISTS | ADAMTS7, MMP7, ADAMTS1 | ALDH1A1 2009/4885MAPT 4378/4885KDM4E 2923/4885 |
| US-11299461-B2 | Pyridin-2-yl alkylamino substituted hydroxamic acid and uses thereof | H1-5, HCAR3, H1-3 | ALDH1A1 2060/4885MAPT 4866/4885KDM4E 1555/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.