Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | GSK3A | P49840 | 3/20 | 0.48 |
| ▸ | GSK3B | P49841 | 3/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.45 |
| ▸ | CDK1 | P06493 | 1/20 | 0.45 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.45 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.45 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.44 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5482630 | 0.91 | HPGD (0.49) | HPGDGSK3AGSK3BMAPK14CYP2D6 | |
| SCHEMBL5481632 | 0.85 | P2RX4 (0.52) | SMN1; SMN2P2RX4AKR1B10AKR1B1CYP2C19 | |
| SCHEMBL7830409 | 0.84 | MAPK14 (0.44) | HPGDGSK3AGSK3BMAPK14CYP2D6 | |
| SCHEMBL25433184 | 0.82 | MAPT (0.51) | TP53CYP3A4AKR1B10AKR1B1CYP2C19 | |
| SCHEMBL4488624 | 0.80 | YTHDC1 (0.44) | HPGDMAPK14TP53SMN1; SMN2CYP3A4 | |
| SCHEMBL7466508 | 0.80 | HPGD (0.55) | HPGDGSK3AGSK3BSMN1; SMN2CYP3A4 | |
| SCHEMBL4494422 | 0.80 | MAPK14 (0.46) | HPGDGSK3AGSK3BMAPK14CYP2D6 | |
| SCHEMBL1584773 | 0.80 | HPGD (0.47) | HPGDGSK3AGSK3BKDM4ESMN1; SMN2 | |
| SCHEMBL9118024 | 0.80 | CYP3A4 (0.51) | HPGDGSK3AGSK3BMAPK14CYP2D6 | |
| SCHEMBL7750738 | 0.80 | HPGD (0.51) | HPGDGSK3AGSK3BKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108341771-B | Preparation method of 3-cyano-2, 6-dihydroxypyridine sodium hydrate | 浙江九洲药业股份有限公司 | 2021-05-11 | — | — | CN | disclosed |
| WO-2006070292-A2 | PYRIMIDINE COMPOUNDS AS ANTI-ICTOGENIC AND/OR ANTI-EPILEPTOGENIC AGENTS | QUEEN'S UNIVERSITY AT KINGSTON (US) | 2006-07-06 | — | — | WO | disclosed |
| US-4171429-A | Pyrimidine to pyrimidine transformation process | RESEARCH CORPORATION (US) | 1979-10-16 | — | — | US | disclosed |