Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 1/20 | 0.52 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.52 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | AR | P10275 | 3/20 | 0.47 |
| ▸ | CFTR | P13569 | 1/20 | 0.46 |
| ▸ | DBH | P09172 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9453625 | 0.86 | KMT2A (0.54) | P2RX4KMT2AMEN1DBHCYP1A2 | |
| SCHEMBL5800712 | 0.85 | HPGD (0.49) | P2RX4AKR1B10AKR1B1KMT2AMEN1 | |
| SCHEMBL5482630 | 0.80 | HPGD (0.49) | AKR1B10AKR1B1KMT2AMEN1CYP2C19 | |
| SCHEMBL5800407 | 0.79 | KMT2A (0.44) | P2RX4KMT2AMEN1ARDBH | |
| SCHEMBL5474617 | 0.77 | ALDH1A1 (0.61) | P2RX4KMT2AMEN1DBHCYP1A2 | |
| SCHEMBL16880622 | 0.77 | P2RX4 (0.52) | P2RX4KMT2AMEN1DBHCYP1A2 | |
| SCHEMBL5475973 | 0.76 | ALDH1A1 (0.49) | P2RX4KMT2AMEN1DBHCYP1A2 | |
| SCHEMBL5797003 | 0.76 | HTT (0.44) | KMT2AMEN1CYP1A2CYP2C19POLB | |
| SCHEMBL7467639 | 0.75 | AKR1B10 (0.54) | AKR1B10AKR1B1KMT2AMEN1POLB | |
| SCHEMBL7460226 | 0.75 | AKR1B10 (0.66) | AKR1B10AKR1B1KMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070010529-A1 | Nitrogenous heterocyclic compounds and medical use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-01-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070010529-A1 | Nitrogenous heterocyclic compounds and medical use thereof | MAPK1, NOS1, NOS2 | P2RX4 672/4885AKR1B10 1316/4885AKR1B1 787/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.