Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 10/20 | 0.49 |
| ▸ | CTSL | P07711 | 14/20 | 0.49 |
| ▸ | CTSS | P25774 | 11/20 | 0.49 |
| ▸ | CTSB | P07858 | 11/20 | 0.49 |
| ▸ | CTSV | O60911 | 5/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6208313 | 0.88 | CTSL (0.53) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6208306 | 0.88 | CTSL (0.53) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL5808560 | 0.87 | ADRB3 (0.46) | — | |
| SCHEMBL5800380 | 0.87 | CTSL (0.52) | CTSKCTSLCTSSCTSB | |
| SCHEMBL5797321 | 0.85 | POLB (0.45) | — | |
| Lithium Ion SCHEMBL5808563 | 0.85 | MEN1 (0.41) | CTSK | |
| SCHEMBL6268990 | 0.84 | CTSK (0.49) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6268987 | 0.84 | CTSK (0.49) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6272581 | 0.83 | JAK2 (0.52) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6272589 | 0.83 | JAK2 (0.52) | CTSKCTSLCTSSCTSBCTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006042103-A2 | REVERSIBLE INHIBITORS OF CATHEPSIN B | AXYS PHARMACEUTICALS, INC. (US) | 2006-04-20 | — | — | WO | claimed |
| WO-2006042103-A2 | REVERSIBLE INHIBITORS OF CATHEPSIN B | AXYS PHARMACEUTICALS, INC. (US) | 2006-04-20 | — | — | WO | disclosed |