Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | SNCA | P37840 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 5/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14920216 | 0.83 | AGPAT2 (0.50) | KDM4EMEN1NPC1MAPTALOX15 | |
| SCHEMBL7086524 | 0.81 | ASIC3 (0.47) | TDP1KDM4EMEN1NPC1GAA | |
| SCHEMBL31175342 | 0.80 | HSD17B14 (0.42) | NPC1POLBKDM4CASIC3LMNA | |
| SCHEMBL6644940 | 0.80 | ALDH1A1 (0.46) | KDM4EMEN1NPC1GAAMAPT | |
| SCHEMBL27859531 | 0.79 | ASIC3 (0.53) | TDP1MEN1GAAMAPTALOX15 | |
| SCHEMBL4919409 | 0.75 | KDM1A (0.70) | TDP1KDM4EMEN1NPC1GAA | |
| SCHEMBL20278400 | 0.75 | ASIC3 (0.44) | KDM4ENPC1GAAMAPTRAB9A | |
| SCHEMBL6642591 | 0.75 | CDK1 (0.50) | KDM4ENPC1RAB9AASIC3ALDH1A1 | |
| SCHEMBL6641629 | 0.75 | CDK1 (0.50) | KDM4ENPC1RAB9AASIC3ALDH1A1 | |
| SCHEMBL5803933 | 0.74 | CDK1 (0.58) | TDP1KDM4EMEN1NPC1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006068410-A1 | NOVEL 3-(2-AMINO-6-PYRIDINYL)-4-HYDROXYPHENYL AMINE DERIVATIVES | LG LIFE SCIENCES, LTD. (KR) | 2006-06-29 | — | — | WO | disclosed |
| WO-2006068410-A1 | NOVEL 3-(2-AMINO-6-PYRIDINYL)-4-HYDROXYPHENYL AMINE DERIVATIVES | LG LIFE SCIENCES, LTD. (KR) | 2006-06-29 | — | — | WO | disclosed |