Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 9/20 | 0.39 |
| ▸ | MDM4 | O15151 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3563022 | 0.90 | MDM2 (0.41) | MDM2MDM4OPRM1OPRL1TSHR | |
| SCHEMBL5803975 | 0.86 | MDM2 (0.34) | MDM2MDM4LMNAMAPTL3MBTL1 | |
| SCHEMBL5801209 | 0.82 | TRPM8 (0.47) | MDM2KDM4ENR1I2MAPTALDH1A1 | |
| SCHEMBL3569300 | 0.76 | CNR2 (0.41) | MDM2MDM4MAPTALDH1A1CES2 | |
| SCHEMBL3564244 | 0.76 | CES2 (0.36) | MDM2MDM4MAPTATML3MBTL1 | |
| SCHEMBL3557436 | 0.76 | PPARG (0.38) | MDM2LMNAMAPTCNR1ALDH1A1 | |
| SCHEMBL3563412 | 0.76 | PPARA (0.38) | MDM2MDM4MAPTATMALDH1A1 | |
| SCHEMBL3568466 | 0.76 | TRPM8 (0.41) | MDM2TSHRCYP2C9CYP2C19KDM4E | |
| SCHEMBL18901157 | 0.74 | NISCH (0.50) | OPRM1SLC6A2SLC6A4ALDH1A1CXCL8 | |
| SCHEMBL3566188 | 0.74 | ATM (0.45) | TSHRCYP2C9CYP2C19KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006063113-A2 | UREAS AS FACTOR XA INHIBITORS | PORTOLA PHARMACEUTICALS, INC. (US) | 2006-06-15 | — | — | WO | claimed |