Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP26A1 | O43174 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PRNP | P04156 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5800376 | 1.00 | CYP26A1 (0.40) | CYP26A1NPC1MEN1KMT2AERCC5 | |
| SCHEMBL5798028 | 0.94 | KMT2A (0.43) | NPC1MEN1KMT2ARAB9AL3MBTL1 | |
| SCHEMBL5799304 | 0.94 | KMT2A (0.43) | NPC1MEN1KMT2ARAB9AL3MBTL1 | |
| SCHEMBL5820016 | 0.90 | KMT2A (0.37) | NPC1MEN1KMT2ARAB9AL3MBTL1 | |
| SCHEMBL5801633 | 0.86 | EPHX2 (0.41) | NPC1MEN1KMT2ARAB9AL3MBTL1 | |
| SCHEMBL5797762 | 0.86 | EPHX2 (0.41) | NPC1MEN1KMT2ARAB9AL3MBTL1 | |
| SCHEMBL5801461 | 0.83 | MAPT (0.37) | KMT2AMAPTSMN1; SMN2ALDH1A1HTT | |
| SCHEMBL5819711 | 0.83 | MAPT (0.37) | KMT2AMAPTSMN1; SMN2ALDH1A1HTT | |
| SCHEMBL5799405 | 0.81 | MAPT (0.41) | NPC1MEN1KMT2ARAB9AL3MBTL1 | |
| SCHEMBL5801549 | 0.81 | MAPT (0.41) | NPC1MEN1KMT2ARAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006030208-A1 | AMINO ACID | UNIVERSITY OF LEEDS (GB) | 2006-03-23 | — | — | WO | claimed |
| WO-2006030208-A1 | AMINO ACID | UNIVERSITY OF LEEDS (GB) | 2006-03-23 | — | — | WO | disclosed |