Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GRN | P28799 | 1/20 | 0.34 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5819711 | 1.00 | MAPT (0.37) | MAPTMAPK1NPSR1TSHRSMN1; SMN2 | |
| SCHEMBL5820016 | 0.85 | KMT2A (0.37) | MAPTHPGDALDH1A1KMT2ATHRB | |
| SCHEMBL5797834 | 0.85 | KMT2A (0.37) | MAPTHPGDALDH1A1KMT2ATHRB | |
| SCHEMBL5799304 | 0.83 | KMT2A (0.43) | MAPTTSHRSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL5798028 | 0.83 | KMT2A (0.43) | MAPTTSHRSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL5801142 | 0.83 | CYP26A1 (0.40) | MAPTSMN1; SMN2HPGDALDH1A1KMT2A | |
| SCHEMBL5800376 | 0.83 | CYP26A1 (0.40) | MAPTSMN1; SMN2HPGDALDH1A1KMT2A | |
| SCHEMBL5801633 | 0.82 | EPHX2 (0.41) | MAPTNPSR1SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL5797762 | 0.82 | EPHX2 (0.41) | MAPTNPSR1SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL5799405 | 0.81 | MAPT (0.41) | MAPTMAPK1NPSR1TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006030208-A1 | AMINO ACID | UNIVERSITY OF LEEDS (GB) | 2006-03-23 | — | — | WO | claimed |
| WO-2006030208-A1 | AMINO ACID | UNIVERSITY OF LEEDS (GB) | 2006-03-23 | — | — | WO | disclosed |