Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 3/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PRNP | P04156 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | SCN1A | P35498 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5798028 | 1.00 | KMT2A (0.43) | KMT2ANPC1MEN1MAPTALDH1A1 | |
| SCHEMBL5801142 | 0.94 | CYP26A1 (0.40) | KMT2ANPC1MEN1MAPTALDH1A1 | |
| SCHEMBL5800376 | 0.94 | CYP26A1 (0.40) | KMT2ANPC1MEN1MAPTALDH1A1 | |
| SCHEMBL5820016 | 0.91 | KMT2A (0.37) | KMT2ANPC1MEN1MAPTALDH1A1 | |
| SCHEMBL5798241 | 0.87 | ALDH1A1 (0.40) | KMT2ANPC1MEN1MAPTALDH1A1 | |
| SCHEMBL5797762 | 0.86 | EPHX2 (0.41) | KMT2ANPC1MEN1MAPTALDH1A1 | |
| SCHEMBL5801633 | 0.86 | EPHX2 (0.41) | KMT2ANPC1MEN1MAPTALDH1A1 | |
| SCHEMBL5801549 | 0.86 | MAPT (0.41) | KMT2ANPC1MEN1MAPTALDH1A1 | |
| SCHEMBL5799405 | 0.86 | MAPT (0.41) | KMT2ANPC1MEN1MAPTALDH1A1 | |
| SCHEMBL5801461 | 0.83 | MAPT (0.37) | KMT2AMAPTALDH1A1SMN1; SMN2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006030208-A1 | AMINO ACID | UNIVERSITY OF LEEDS (GB) | 2006-03-23 | — | — | WO | claimed |
| WO-2006030208-A1 | AMINO ACID | UNIVERSITY OF LEEDS (GB) | 2006-03-23 | — | — | WO | disclosed |