Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5797762 | 1.00 | EPHX2 (0.41) | EPHX2PPARGPTPN1NPSR1NPC1 | |
| SCHEMBL5797287 | 0.89 | GPR35 (0.35) | EPHX2PPARGNPSR1SMN1; SMN2POLB | |
| SCHEMBL5797971 | 0.89 | GPR35 (0.35) | EPHX2PPARGNPSR1SMN1; SMN2POLB | |
| SCHEMBL5797834 | 0.89 | KMT2A (0.37) | NPC1RAB9APOLBMAPTMEN1 | |
| SCHEMBL5820016 | 0.89 | KMT2A (0.37) | NPC1RAB9APOLBMAPTMEN1 | |
| SCHEMBL5799304 | 0.86 | KMT2A (0.43) | NPC1RAB9ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL5798028 | 0.86 | KMT2A (0.43) | NPC1RAB9ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL5801142 | 0.86 | CYP26A1 (0.40) | NPC1RAB9ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL5800376 | 0.86 | CYP26A1 (0.40) | NPC1RAB9ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL5814731 | 0.83 | ALDH1A1 (0.40) | NPC1RAB9ASMN1; SMN2POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006030208-A1 | AMINO ACID | UNIVERSITY OF LEEDS (GB) | 2006-03-23 | — | — | WO | claimed |
| WO-2006030208-A1 | AMINO ACID | UNIVERSITY OF LEEDS (GB) | 2006-03-23 | — | — | WO | disclosed |