Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.34 |
| ▸ | TAS1R2 | Q8TE23 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | NOS1 | P29475 | 2/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL5144834 | 0.97 | CYP3A4 (0.34) | CYP3A4CYP2C9CYP2C19ALDH1A1MAPT | |
| SCHEMBL16206286 | 0.81 | CYP3A4 (0.32) | CYP3A4CYP2C9CYP2C19ALDH1A1MAPT | |
| SCHEMBL6562346 | 0.79 | CYP3A4 (0.39) | CYP3A4CYP2C9CYP2C19ALDH1A1TAS1R3 | |
| SCHEMBL12497935 | 0.77 | — | — | |
| SCHEMBL22508527 | 0.74 | CYP3A4 (0.35) | CYP3A4CYP2C9CYP2C19ALDH1A1TAS1R3 | |
| SCHEMBL4850022 | 0.74 | CYP3A4 (0.44) | CYP3A4CYP2C9CYP2C19ALDH1A1MAPT | |
| SCHEMBL25126121 | 0.72 | — | — | |
| SCHEMBL22604080 | 0.72 | — | — | |
| SCHEMBL27859504 | 0.72 | NOS3 (0.33) | TAS1R3TAS1R1TAS1R2NOS1NOS3 | |
| SCHEMBL27791251 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0354553-A2 | Aryl cyanoguanidines: potassium channel activators and method of making same | E.R. SQUIBB & SONS, INC. (US) | 1990-02-14 | — | — | EP | claimed |
| US-20210379091-A1 | USE OF CATIONIC STEROIDAL ANTIMICROBIAL COMPOUNDS TO DEACTIVATE CORONAVIRUS | BRIGHAM YOUNG UNIVERSITY (US) | 2021-12-09 | — | — | US | disclosed |
| US-9867836-B2 | Lavage and/or infusion using CSA compounds for increasing fertility in a mammal | BRIGHAM YOUNG UNIVERSITY (US) | 2018-01-16 | — | — | US | disclosed |
| US-9686966-B2 | Methods and apparatus for cleaning or disinfecting a water delivery system | BRIGHAM YOUNG UNIVERSITY (US) | 2017-06-27 | — | — | US | disclosed |
| WO-2006088798-A2 | MODULATION OF HYPOTHALAMIC ATP-SENSITIVE POTASSIUM CHANNELS | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2006-08-24 | — | — | WO | disclosed |
| EP-0354553-A2 | Aryl cyanoguanidines: potassium channel activators and method of making same | E.R. SQUIBB & SONS, INC. (US) | 1990-02-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210379091-A1 | USE OF CATIONIC STEROIDAL ANTIMICROBIAL COMPOUNDS TO DEACTIVATE CORONAVIRUS | CD14, CCL5, MIF | CYP3A4 348/4885CYP2C9 464/4885CYP2C19 92/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.