Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 5/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2963786 | 0.84 | HTR4 (0.53) | HTR4SLC6A2POLB | |
| SCHEMBL6584714 | 0.84 | HTR4 (0.54) | HTR4SLC6A2POLB | |
| SCHEMBL7062555 | 0.79 | SLC6A2 (0.56) | HTR4SLC6A2POLB | |
| SCHEMBL28353847 | 0.76 | HTR4 (0.47) | HTR4SLC6A2 | |
| SCHEMBL13322673 | 0.74 | POLB (0.46) | HTR4SLC6A2POLB | |
| SCHEMBL6588314 | 0.72 | TMEM97 (0.50) | HTR4 | |
| SCHEMBL12139324 | 0.72 | SLC6A2 (0.50) | HTR4SLC6A2POLB | |
| SCHEMBL27836296 | 0.71 | POLB (0.53) | SLC6A2POLB | |
| SCHEMBL5741602 | 0.71 | SLC6A2 (0.47) | HTR4SLC6A2POLB | |
| SCHEMBL19337265 | 0.70 | HTR4 (0.47) | HTR4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916174-A | Compositions and methods for preventing stress-induced phobia, depression-like, and anxiety-like behaviors | 纽约市哥伦比亚大学理事会 | 2023-04-04 | — | — | CN | disclosed |
| EP-1664036-A1 | BENZIMIDAZOLONE COMPOUNDS HAVING 5-HT4 RECEPTOR AGONISTIC ACTIVITY | Pfizer, Inc. (US) | 2006-06-07 | — | — | EP | disclosed |
| WO-2005021539-A1 | BENZIMIDAZOLONE COMPOUNDS HAVING 5-HT4 RECEPTOR AGONISTIC ACTIVITY | PFIZER JAPAN, INC. (JP) | 2005-03-10 | — | — | WO | disclosed |