SCHEMBL19337265

SCHEMBL19337265

CC(C)n1c(=O)n(C(=N)C2N=C2Cl)c2ccccc21

nearest known ligand 0.47

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR4 Q13639 5/20 0.47
SLC6A2 P23975 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19337255 0.78 TMEM97 (0.43) HTR4
SCHEMBL6584714 0.75 HTR4 (0.54) HTR4SLC6A2
SCHEMBL2963786 0.71 HTR4 (0.53) HTR4SLC6A2
SCHEMBL5801271 0.70 HTR4 (0.52) HTR4SLC6A2
SCHEMBL7062555 0.70 SLC6A2 (0.56) HTR4SLC6A2
SCHEMBL28353847 0.65 HTR4 (0.47) HTR4SLC6A2
SCHEMBL12139324 0.64 SLC6A2 (0.50) HTR4SLC6A2
SCHEMBL27836296 0.62 POLB (0.53) SLC6A2
SCHEMBL5741602 0.62 SLC6A2 (0.47) HTR4SLC6A2
SCHEMBL13322673 0.62 POLB (0.46) HTR4SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3216786-A1 PYRIMIDINE OR PYRIDINE COMPOUNDS, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USES THEREOF Shanghai Shaletech Technology Co., Ltd. (CN) 2017-09-13 EP disclosed