Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.54 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.47 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.47 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28671968 | 0.91 | MAPT (0.53) | MAPTGAAGFERSIRT2FFAR1 | |
| SCHEMBL9425104 | 0.85 | FFAR1 (0.69) | MAPTFFAR1HTTFFAR4KEAP1 | |
| SCHEMBL5813249 | 0.85 | SIRT1 (0.60) | MAPTGAAGFERSIRT2PRMT1 | |
| SCHEMBL5020712 | 0.83 | FFAR1 (0.69) | MAPTPRMT1FFAR1HTTALDH1A1 | |
| SCHEMBL2593 | 0.82 | KEAP1 (0.67) | MAPTPRMT1FFAR1HTTCASP3 | |
| SCHEMBL27463865 | 0.81 | MAPT (0.58) | MAPTGAAGFERSIRT2HTT | |
| Hydrochloric Acid SCHEMBL6952080 | 0.81 | KEAP1 (0.64) | MAPTPRMT1FFAR1HTTALDH1A1 | |
| Hydrochloric Acid SCHEMBL3308277 | 0.81 | KEAP1 (0.64) | MAPTPRMT1FFAR1HTTALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL10416110 | 0.81 | KEAP1 (0.64) | MAPTPRMT1FFAR1HTTALDH1A1 | |
| Hydrazine SCHEMBL28262207 | 0.81 | KEAP1 (0.64) | MAPTPRMT1FFAR1HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006094800-A2 | CASCADE REACTION PROCESS | SYNTHON B.V. (NL) | 2006-09-14 | — | — | WO | disclosed |