Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.60 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.50 |
| ▸ | RHOA | P61586 | 1/20 | 0.50 |
| ▸ | AURKA | O14965 | 1/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.49 |
| ▸ | NEK2 | P51955 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5801699 | 0.85 | MAPT (0.55) | SIRT2MAPTGAAFFAR1HTT | |
| SCHEMBL5777508 | 0.84 | ITGB3 (0.56) | SIRT1MAPTGAAFFAR1ITGB3 | |
| SCHEMBL5491571 | 0.83 | SIRT1 (0.60) | SIRT1SIRT2FFAR1RHOAAURKA | |
| SCHEMBL28057053 | 0.82 | AURKA (0.64) | SIRT1SIRT2FFAR1RHOAAURKA | |
| SCHEMBL2593 | 0.78 | KEAP1 (0.67) | MAPTFFAR1HTTALDH1A1PRMT1 | |
| SCHEMBL18772373 | 0.78 | FFAR1 (0.52) | FFAR1PRMT1 | |
| SCHEMBL3743153 | 0.77 | FFAR1 (0.59) | SIRT1MAPTFFAR1RHOAITGB3 | |
| SCHEMBL28671968 | 0.77 | MAPT (0.53) | SIRT2MAPTGAAFFAR1HTT | |
| Hydrochloric Acid SCHEMBL3308277 | 0.77 | KEAP1 (0.64) | MAPTFFAR1HTTALDH1A1PRMT1 | |
| Ammonia Solution, Strong SCHEMBL10416110 | 0.77 | KEAP1 (0.64) | MAPTFFAR1HTTALDH1A1PRMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006094800-A2 | CASCADE REACTION PROCESS | SYNTHON B.V. (NL) | 2006-09-14 | — | — | WO | disclosed |