Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 16/20 | 0.69 |
| ▸ | MAOA | P21397 | 9/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10750881 | 0.88 | MAOB (0.74) | MAOBMAOA | |
| SCHEMBL16110038 | 0.88 | MEN1 (0.64) | MAOBMEN1PKMKMT2A | |
| SCHEMBL29853714 | 0.88 | MEN1 (0.64) | MAOBMEN1PKMKMT2A | |
| SCHEMBL564731 | 0.86 | MAOB (0.55) | MAOBMAOAMEN1PKMKMT2A | |
| SCHEMBL26768249 | 0.84 | ALDH1A1 (0.53) | MAOBMEN1PKMKMT2A | |
| SCHEMBL560607 | 0.84 | MAOB (0.81) | MAOBMAOACASP3SENP8SENP7 | |
| SCHEMBL2785214 | 0.84 | MAOB (0.71) | MAOBMAOA | |
| SCHEMBL23887772 | 0.82 | NMT2 (0.56) | MAOBMAOAMEN1PKMKMT2A | |
| SCHEMBL30367618 | 0.82 | NMT2 (0.56) | MAOBMAOAMEN1PKMKMT2A | |
| SCHEMBL567416 | 0.82 | MAOB (1.00) | MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006067412-A1 | CHEMICAL PROCESSES FOR THE PREPARATION OF A COLCHINOL DERIVATIVE AND INTERMEDIATES | ASTRAZENECA AB (SE) | 2006-06-29 | — | — | WO | disclosed |
| WO-2006067416-A1 | CHEMICAL PROCESSES AND INTERMEDIATES | ASTRAZENECA AB (SE) | 2006-06-29 | — | — | WO | disclosed |