Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 13/20 | 0.81 |
| ▸ | MAOA | P21397 | 8/20 | 0.74 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.62 |
| ▸ | PTGES | O14684 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29945833 | 0.89 | MAOB (1.00) | MAOBMAOAMAPTL3MBTL1HTT | |
| SCHEMBL567416 | 0.89 | MAOB (1.00) | MAOBMAOAMAPTL3MBTL1HTT | |
| SCHEMBL343794 | 0.88 | MCL1 (0.78) | MAOBMAOAMCL1PTGESCYP2C19 | |
| SCHEMBL17848310 | 0.87 | MAOB (0.77) | MAOBMAOAMAPTL3MBTL1HTT | |
| SCHEMBL27852320 | 0.85 | MAOB (0.63) | MAOBMAOAMCL1PTGESMAPT | |
| SCHEMBL710202 | 0.85 | MAOB (0.63) | MAOBMAOAMCL1PTGESMAPT | |
| SCHEMBL754206 | 0.85 | MAOB (0.82) | MAOBMAOA | |
| SCHEMBL29717105 | 0.85 | MAOB (0.63) | MAOBMAOAMCL1PTGESMAPT | |
| SCHEMBL2785214 | 0.85 | MAOB (0.71) | MAOBMAOAMAPTL3MBTL1CYP2C19 | |
| SCHEMBL7348486 | 0.85 | MAOB (0.83) | MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 148 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107935972-B | 5- [ 2-hydroxy-3- (isopropylamino) propoxy ] benzofuran derivative and application thereof | 沈阳药科大学 | 2020-06-02 | — | — | CN | claimed |
| CN-107857748-B | 5- [ 2-hydroxy-3- (alkylamino) propoxy ] benzofuran compound and application thereof | 沈阳药科大学 | 2020-06-02 | — | — | CN | claimed |
| US-12473283-B2 | Compounds and their use | DEBIOPHARM INTERNATIONAL S.A. (CH) | 2025-11-18 | — | — | US | disclosed |
| US-12297176-B2 | Compounds and methods for inhibiting EMT pathways to treat cancer, organ fibrosis and metabolic disorders | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2025-05-13 | — | — | US | disclosed |
| EP-4549424-A1 | NEW LITHIUM EXTRACTING AGENT AND LIQUID ORGANIC MIXTURE THEREOF, AND METHOD FOR EXTRACTING LITHIUM BY MEANS OF EXTRACTION | Beijing Salt Lake Technology Development Company Limited (CN) | 2025-05-07 | — | — | EP | disclosed |
| US-20240408214-A1 | NANOPARTICULATE MONOBENZONE FOR TREATING MELANOMA | NORTHWESTERN UNIVERSITY | 2024-12-12 | — | — | US | disclosed |
| CN-115151541-B | Novel compounds and uses thereof | 德彪药业国际股份公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-117534556-A | Novel lithium extractant, liquid organic mixture thereof and method for extracting lithium by extraction | 北京索特莱克科技发展有限公司 | 2024-02-09 | — | — | CN | disclosed |
| WO-2024027447-A1 | NEW LITHIUM EXTRACTING AGENT AND LIQUID ORGANIC MIXTURE THEREOF, AND METHOD FOR EXTRACTING LITHIUM BY MEANS OF EXTRACTION | 北京索特莱克科技发展有限公司 | 2024-02-08 | — | — | WO | disclosed |
| US-11724999-B2 | Inhibitors of RAS-effector protein interactions | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2023-08-15 | — | — | US | disclosed |
| US-11724999-B2 | Inhibitors of RAS-effector protein interactions | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2023-08-15 | — | — | US | disclosed |
| EP-0391624-A1 | Substituted 1-[3-heteroarylmethoxy)phenyl] alkanols and related compounds in the treatment of asthma, arthritis and related diseases | PFIZER INC. (US) | 1990-10-10 | — | — | EP | disclosed |
| EP-0056172-B1 | PHENOXY- AND THIOPHENOXY COMPOUNDS, METHODS FOR THEIR PREPARATION AND PHARMACEUTICAL FORMULATIONS CONTAINING THEM | FISONS plc (GB) | 1985-04-03 | — | — | EP | disclosed |
| US-4479007-A | Chroman-4-ones and process for preparing same | BAYER AKTIENGESELLSCHAFT (DE) | 1984-10-23 | — | — | US | disclosed |
| US-4415741-A | REACTING O-HYDROXYACETOPHENONE AND CYCLOPENTANONE | BAYER AKTIENGESELLSCHAFT (DE) | 1983-11-15 | — | — | US | disclosed |
| EP-0056172-A2 | Phenoxy- and thiophenoxy compounds, methods for their preparation and pharmaceutical formulations containing them | FISONS plc (GB) | 1982-07-21 | — | — | EP | disclosed |
| US-4307020-A | REACTING AN 0-HYDROXYACETOPHENONE WITH A GLYOXYLIC ACID | BAYER AKTIENGESELLSCHAFT (DE) | 1981-12-22 | — | — | US | disclosed |
| US-4285965-A | FUNGICIDES AND INSECTICIDES FOR PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 1981-08-25 | — | — | US | disclosed |
| EP-0000377-B1 | PROCESS FOR THE PREPARATION OF CHROMONE DERIVATIVES, NEW CHROMONE DERIVATIVES AND THEIR USE AS PLANT-PROTECTING AGENTS | BAYER AG (DE) | 1981-01-21 | — | — | EP | disclosed |
| US-4189498-A | FUNGICIDES, ARTHROPODICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1980-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12297176-B2 | Compounds and methods for inhibiting EMT pathways to treat cancer, organ fibrosis and metabolic disorders | HGF, SMAD3, HRAS | MAOB 4207/4885MAOA 4663/4885MCL1 1083/4885 |
| US-11724999-B2 | Inhibitors of RAS-effector protein interactions | KRAS, NRAS, HRAS | MAOB 4420/4885MAOA 4589/4885MCL1 344/4885 |
| US-12473283-B2 | Compounds and their use | LSS, PGLS, LDHB | MAOB 917/4885MAOA 2023/4885MCL1 629/4885 |
| US-20240408214-A1 | NANOPARTICULATE MONOBENZONE FOR TREATING MELANOMA | TYR, CD47, SDHB | MAOB 6/4885MAOA 98/4885MCL1 14/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.