Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | RXRG | P48443 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5802121 | 1.00 | PTGS2 (0.34) | PTGS2PPARGPPARAALDH1A1HCAR2 | |
| SCHEMBL10526912 | 0.84 | CES2 (0.46) | PPARGPPARAALDH1A1 | |
| SCHEMBL10525099 | 0.84 | CES2 (0.46) | PPARGPPARAALDH1A1 | |
| SCHEMBL10526906 | 0.84 | CES2 (0.46) | PPARGPPARAALDH1A1 | |
| SCHEMBL11105180 | 0.81 | — | — | |
| SCHEMBL1721778 | 0.77 | MAPT (0.48) | ALDH1A1LMNA | |
| SCHEMBL11110921 | 0.77 | DGKA (0.41) | PPARGPPARAALDH1A1 | |
| SCHEMBL11104748 | 0.77 | DGKA (0.41) | PPARGPPARAALDH1A1 | |
| SCHEMBL5801514 | 0.76 | PPARG (0.33) | PPARGPPARAALDH1A1HCAR2RXRA | |
| SCHEMBL5801512 | 0.76 | PPARG (0.33) | PPARGPPARAALDH1A1HCAR2RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006057503-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPARϜ AND PPARα, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES, LTD. (KR) | 2006-06-01 | — | — | WO | disclosed |