Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | BCR | P11274 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5802848 | 0.88 | TSHR (0.46) | HTTLMNATSHRTDP1MAPT | |
| SCHEMBL5802845 | 0.88 | TSHR (0.46) | HTTLMNATSHRTDP1MAPT | |
| SCHEMBL5802842 | 0.88 | TSHR (0.46) | HTTLMNATSHRTDP1MAPT | |
| SCHEMBL5802840 | 0.88 | TSHR (0.46) | HTTLMNATSHRTDP1MAPT | |
| SCHEMBL5806417 | 0.88 | LMNA (0.46) | HTTLMNAVCAM1TDP1MAPT | |
| SCHEMBL5802478 | 0.88 | LMNA (0.46) | HTTLMNAVCAM1TDP1MAPT | |
| SCHEMBL5801804 | 0.88 | LMNA (0.46) | HTTLMNAVCAM1TDP1MAPT | |
| SCHEMBL5802176 | 0.87 | POLB (0.45) | HTTLMNAVCAM1TSHRMAPT | |
| SCHEMBL5815714 | 0.83 | — | — | |
| SCHEMBL5804956 | 0.82 | LMNA (0.46) | HTTLMNAVCAM1TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006079857-A1 | DIARYL ACETIC ACID DERIVATIVES AND THE PREPARATION THEREOF | SANOFI-AVENTIS (FR) | 2006-08-03 | — | — | WO | disclosed |