Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 2/20 | 0.46 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.46 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.46 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.46 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | RAF1 | P04049 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5819216 | 0.85 | CDK1 (0.47) | CDK1CCNB2CCNB1GSK3BCDK5 | |
| Hydrochloric Acid SCHEMBL5813979 | 0.84 | CDK1 (0.47) | CDK1CCNB2CCNB1GSK3BCDK5 | |
| SCHEMBL5815923 | 0.82 | CDK1 (0.56) | CDK1CCNB2CCNB1GSK3BCDK5 | |
| SCHEMBL5819011 | 0.82 | CDK1 (0.55) | CDK1CCNB2CCNB1GSK3BCDK5 | |
| SCHEMBL5820378 | 0.76 | CDK1 (0.64) | CDK1CCNB2CCNB1GSK3BCCNB3 | |
| SCHEMBL5802955 | 0.74 | CDK1 (0.53) | CDK1CCNB2CCNB1GSK3BCDK5 | |
| SCHEMBL5823198 | 0.74 | CDK1 (0.57) | CDK1CCNB2CCNB1GSK3BCDK5 | |
| SCHEMBL5806193 | 0.74 | CDK1 (0.56) | CDK1CCNB2CCNB1GSK3BCDK5 | |
| SCHEMBL5802551 | 0.72 | CDK1 (0.51) | CDK1CCNB2CCNB1GSK3BCDK5 | |
| SCHEMBL5803817 | 0.70 | CDK1 (0.64) | CDK1CCNB2CCNB1GSK3BCDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006089874-A1 | BENZO[2,3]AZEPINO[4,5-B]INDOL-6-ONES | GPC BIOTECH AG (DE) | 2006-08-31 | — | — | WO | claimed |