Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4821713 | 0.84 | HTR1A (0.47) | HTR1ASLC6A4KMT2ATSHRKCNH2 | |
| SCHEMBL5107391 | 0.81 | KMT2A (0.43) | HTR1ASLC6A4KMT2ATSHRKCNH2 | |
| SCHEMBL24398651 | 0.78 | HTR1A (0.47) | HTR1ASLC6A4KMT2ATSHRKCNH2 | |
| SCHEMBL11212676 | 0.77 | TSHR (0.61) | HTR1ASLC6A4KMT2ATSHRKCNH2 | |
| SCHEMBL5428241 | 0.77 | HTR1A (0.42) | HTR1ASLC6A4KMT2ATSHRKCNH2 | |
| SCHEMBL9092776 | 0.76 | KMT2A (0.50) | HTR1ASLC6A4KMT2ATSHRKCNH2 | |
| SCHEMBL27558296 | 0.75 | MAOA (0.43) | HTR1ASLC6A4KMT2ATSHRKCNH2 | |
| SCHEMBL5112766 | 0.75 | PPARG (0.49) | KMT2ATSHRMAPTLMNARXFP1 | |
| SCHEMBL4031991 | 0.75 | CYSLTR2 (0.42) | HTR1ASLC6A4KMT2ATSHRKCNH2 | |
| SCHEMBL5807544 | 0.74 | MAPT (0.47) | KMT2AMAPTLMNAPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006082495-A1 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | RANBAXY LABORATORIES LIMITED (IN) | 2006-08-10 | — | — | WO | claimed |
| WO-2006082495-A1 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | RANBAXY LABORATORIES LIMITED (IN) | 2006-08-10 | — | — | WO | disclosed |