Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.40 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28746962 | 0.93 | MAOB (0.45) | MAOAMAOBTSHRKCNH2HTR1A | |
| SCHEMBL27576358 | 0.89 | MAOA (0.41) | MAOAMAOBTSHRKCNH2HTR1A | |
| SCHEMBL5431705 | 0.80 | PPARG (0.48) | TSHRKMT2ACYSLTR2CYSLTR1 | |
| SCHEMBL27576359 | 0.79 | L3MBTL1 (0.47) | TSHRHTR1AGRM5 | |
| SCHEMBL5457078 | 0.76 | TSHR (0.41) | TSHRKMT2ACYSLTR2CYSLTR1GRM5 | |
| SCHEMBL5803100 | 0.75 | HTR1A (0.45) | MAOAMAOBTSHRKCNH2HTR1A | |
| SCHEMBL5107391 | 0.74 | KMT2A (0.43) | MAOAMAOBTSHRKCNH2HTR1A | |
| SCHEMBL5104081 | 0.72 | PPARG (0.55) | — | |
| SCHEMBL11212676 | 0.71 | TSHR (0.61) | TSHRKCNH2HTR1AKMT2AGRM5 | |
| SCHEMBL5428241 | 0.71 | HTR1A (0.42) | MAOAMAOBTSHRKCNH2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1353699-A | Substituted bicyclic heterocycles, process for their preparation and their use as antiobesity and hypocholesterolemic agents | REDDY RESEARCH FOUNDATION (IN) | 2002-06-12 | — | — | CN | claimed |
| CN-1353699-A | Substituted bicyclic heterocycles, process for their preparation and their use as antiobesity and hypocholesterolemic agents | REDDY RESEARCH FOUNDATION (IN) | 2002-06-12 | — | — | CN | disclosed |