SCHEMBL580314

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL7259092	0.86	CASP1 (0.71)	CASP1KDM4ELMNASMN1; SMN2PDE10A
	SCHEMBL1752817	0.86	CASP1 (1.00)	CASP1KDM4E
	SCHEMBL7255661	0.85	CASP1 (0.69)	CASP1ALDH1A1
	SCHEMBL27225888	0.85	CASP1 (0.56)	CASP1KDM4ESMN1; SMN2DHODHHSD17B10
	SCHEMBL30850823	0.85	CASP1 (0.56)	CASP1KDM4ESMN1; SMN2DHODHHSD17B10
	SCHEMBL8949196	0.81	CASP1 (0.77)	CASP1HSD17B10ALDH1A1HIF1A
	SCHEMBL30448360	0.78	DHODH (0.61)	CASP1DHODH
	SCHEMBL7255590	0.76	CASP1 (0.57)	CASP1DHODH
	SCHEMBL530338	0.76	CASP1 (0.57)	CASP1KDM4ELMNASMN1; SMN2ALDH1A1
	SCHEMBL581664	0.75	CASP1 (0.56)	CASP1KDM4ELMNASMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.