Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 14/20 | 0.57 |
| ▸ | DRD3 | P35462 | 14/20 | 0.57 |
| ▸ | DRD4 | P21917 | 6/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5804054 | 1.00 | DRD2 (0.57) | DRD2DRD3DRD4MEN1KMT2A | |
| SCHEMBL6337111 | 0.89 | DRD2 (0.60) | DRD2DRD3DRD4MEN1KMT2A | |
| SCHEMBL6336517 | 0.89 | DRD2 (0.60) | DRD2DRD3DRD4MEN1KMT2A | |
| SCHEMBL5804077 | 0.87 | HTR1A (0.52) | DRD2DRD3DRD4HTR1A | |
| SCHEMBL6346693 | 0.85 | DRD3 (0.60) | DRD2DRD3DRD4 | |
| SCHEMBL6796054 | 0.83 | DRD2 (0.55) | DRD2DRD3DRD4 | |
| SCHEMBL5217173 | 0.83 | DRD2 (0.55) | DRD2DRD3DRD4 | |
| SCHEMBL6344244 | 0.81 | DRD2 (0.64) | DRD2DRD3DRD4MEN1KMT2A | |
| SCHEMBL6596458 | 0.79 | DRD2 (0.54) | DRD2DRD3DRD4 | |
| SCHEMBL3387809 | 0.78 | DRD2 (0.46) | DRD2DRD3DRD4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006016245-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-02-16 | — | — | WO | disclosed |