Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.52 |
| ▸ | DRD2 | P14416 | 7/20 | 0.42 |
| ▸ | DRD3 | P35462 | 7/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5804054 | 0.87 | DRD2 (0.57) | HTR1ADRD2DRD3DRD4 | |
| SCHEMBL5804053 | 0.87 | DRD2 (0.57) | HTR1ADRD2DRD3DRD4 | |
| SCHEMBL5807853 | 0.77 | HTR1A (0.49) | HTR1ADRD2DRD3DRD4 | |
| SCHEMBL3387783 | 0.76 | DRD2 (0.51) | HTR1ADRD2DRD3DRD4 | |
| SCHEMBL5790451 | 0.75 | HTR1A (0.60) | HTR1ADRD2DRD3DRD4 | |
| SCHEMBL5808854 | 0.75 | HTR1A (0.60) | HTR1ADRD2DRD3DRD4 | |
| SCHEMBL6336517 | 0.75 | DRD2 (0.60) | HTR1ADRD2DRD3DRD4 | |
| SCHEMBL6337111 | 0.75 | DRD2 (0.60) | HTR1ADRD2DRD3DRD4 | |
| SCHEMBL6346693 | 0.75 | DRD3 (0.60) | DRD2DRD3DRD4 | |
| SCHEMBL3391699 | 0.74 | DRD2 (0.44) | HTR1ADRD2DRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006016245-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-02-16 | — | — | WO | claimed |
| WO-2006016245-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-02-16 | — | — | WO | disclosed |