SCHEMBL5804133

SCHEMBL5804133

COC(=O)NC([C]=O)CO

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 1/20 0.34
ACACB O00763 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5804135 1.00 TGFBR1 (0.34) TGFBR1ACACB
SCHEMBL6957947 0.83 ACACB (0.34) ACACB
SCHEMBL1994817 0.81 ACACB (0.30) ACACB
SCHEMBL1994818 0.81 ACACB (0.30) ACACB
SCHEMBL3212391 0.80 CA1 (0.46)
SCHEMBL2405498 0.80 CA1 (0.46)
SCHEMBL1991647 0.79 EPHX1 (0.34) ACACB
SCHEMBL27509909 0.79 ALDH1A1 (0.34) ACACB
SCHEMBL27880184 0.79 SLC22A6 (0.31)
SCHEMBL7766005 0.79 SMN1; SMN2 (0.45)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006015183-A2 PHARMACEUTICAL COMPOSITIONS FOR TREATING DISORDERS OF THE SKIN AXONYX, INC. (US) 2006-02-09 WO claimed