Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6037528 | 0.84 | ALOX5 (0.42) | TDP1ALDH1A1TP53ALOX15TSHR | |
| SCHEMBL13871569 | 0.82 | RAB9A (0.42) | TDP1CYP3A4ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL6037494 | 0.82 | NPSR1 (0.41) | TDP1CYP3A4ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL2895073 | 0.78 | CA1 (0.31) | PARP10CA1CA2 | |
| SCHEMBL13734403 | 0.72 | ALDH1A1 (0.52) | TDP1CYP3A4ALDH1A1MAPK1TP53 | |
| SCHEMBL65464 | 0.72 | ALDH1A1 (0.44) | TDP1CYP3A4ALDH1A1MAPK1TP53 | |
| SCHEMBL11297057 | 0.71 | CYP3A4 (0.41) | TDP1CYP3A4ALDH1A1MAPK1TP53 | |
| SCHEMBL23246120 | 0.71 | HCAR2 (0.34) | ALDH1A1KDM4E | |
| SCHEMBL9233431 | 0.70 | ALDH1A1 (0.42) | TDP1CYP3A4ALDH1A1MAPK1TP53 | |
| SCHEMBL16706030 | 0.69 | TDP1 (0.52) | TDP1CYP3A4ALDH1A1MAPK1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1615925-A1 | IMIDAZOPYRIDINE DERIVATIVES AS MELANOCORTIN RECEPTOR AGONISTS | Société de Conseils de Recherches et d'Applications Scientifiques ( S.C.R.A.S.) (FR) | 2006-01-18 | — | — | EP | disclosed |
| EP-1599167-A2 | NOVEL BENZIMIDAZOLE AND IMIDAZOPYRIDINE DERIVATIVES AND USE THEREOF AS A MEDICAMENT | Société de Conseils de Recherches et d'Applications Scientifiques ( S.C.R.A.S.) (FR) | 2005-11-30 | — | — | EP | disclosed |
| WO-2004089951-A1 | IMIDAZOPYRIDINE DERIVATIVES HAVING AN AFFINITY FOR MELANOCORTIN RECEPTORS | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2004-10-21 | — | — | WO | disclosed |
| WO-2004075823-A2 | NOVEL BENZIMIDAZOLE AND IMIDAZOPYRIDINE DERIVATIVES AND USE THEREOF AS A MEDICAMENT | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2004-09-10 | — | — | WO | disclosed |