Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 9/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.47 |
| ▸ | DRD1 | P21728 | 2/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | HRH1 | P35367 | 2/20 | 0.47 |
| ▸ | DRD3 | P35462 | 2/20 | 0.47 |
| ▸ | HTR2B | P41595 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3131844 | 0.81 | OPRM1 (0.44) | OPRM1CHRM2CHRM4CHRM5ADRA2A | |
| SCHEMBL4826291 | 0.74 | OPRM1 (0.47) | OPRM1CHRM2CHRM4CHRM5ADRA2A | |
| SCHEMBL1742214 | 0.73 | OPRM1 (0.46) | OPRM1CHRM2CHRM4CHRM5ADRA2A | |
| SCHEMBL29785592 | 0.73 | OPRM1 (0.46) | OPRM1CHRM2CHRM4CHRM5ADRA2A | |
| SCHEMBL29785562 | 0.73 | DRD2 (0.52) | OPRM1CHRM2CHRM4CHRM5ADRA2A | |
| SCHEMBL3132955 | 0.73 | DRD2 (0.52) | OPRM1CHRM2CHRM4CHRM5ADRA2A | |
| SCHEMBL85392 | 0.72 | OPRM1 (0.48) | OPRM1CHRM2CHRM4CHRM5ADRA2A | |
| SCHEMBL71975 | 0.72 | CTDSP1 (0.49) | KMT2AMEN1OPRD1GAAMAPT | |
| SCHEMBL14560492 | 0.71 | RAB9A (0.55) | OPRM1CHRM2CHRM4CHRM5ADRA2A | |
| SCHEMBL8495166 | 0.71 | KMT2A (0.54) | OPRM1CHRM2CHRM4CHRM5ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006072353-A1 | AZETIDINE-SUBSTITUTED PYRAZOLINES AS PAR-1 ANTAGONISTS | BAYER HEALTHCARE AG (DE) | 2006-07-13 | — | — | WO | disclosed |