Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3039993 | 0.80 | EPHX1 (0.49) | ALDH1A1EPHX1GAAKMT2AMEN1 | |
| SCHEMBL1951584 | 0.72 | GAA (0.41) | ALDH1A1CA1CA2EPHX1GAA | |
| SCHEMBL2813531 | 0.72 | HDAC4 (0.42) | ALDH1A1EPHX1GAAKMT2ABTK | |
| SCHEMBL2813537 | 0.72 | HDAC4 (0.42) | ALDH1A1EPHX1GAAKMT2ABTK | |
| SCHEMBL4552317 | 0.72 | HSD11B1 (0.44) | ALDH1A1EPHX1GAAKMT2AMEN1 | |
| SCHEMBL31419036 | 0.71 | GAA (0.45) | CA12CA14CA1CA2EPHX1 | |
| SCHEMBL3039099 | 0.71 | CTSS (0.42) | ALDH1A1CA1CA7CA2EPHX1 | |
| SCHEMBL7129642 | 0.71 | ALDH1A1 (0.59) | ALDH1A1KMT2AMEN1LMNATSHR | |
| SCHEMBL13943891 | 0.70 | HSD11B1 (0.45) | ALDH1A1EPHX1GAAKMT2AMEN1 | |
| SCHEMBL22403974 | 0.70 | CA12 (0.50) | CA12CA14CA1CA7CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1713822-A2 | HCV NS-3 SERINE PROTEASE INHIBITORS | Medivir Aktiebolag (SE) | 2006-10-25 | — | — | EP | disclosed |
| WO-2005073216-A2 | HCV NS-3 SERINE PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2005-08-11 | — | — | WO | disclosed |