SCHEMBL5804916

SCHEMBL5804916

CCCC[C@H](NC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21)C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 5/20 0.61
▸ HLCS P50747 3/20 0.60
▸ MEN1 O00255 1/20 0.60
▸ ABL1 P00519 1/20 0.60
▸ LMNA P02545 1/20 0.60
▸ PKM P14618 1/20 0.60
▸ IDE P14735 1/20 0.60
▸ MAPK1 P28482 1/20 0.60
▸ KMT2A Q03164 1/20 0.60
▸ RIN1 Q13671 1/20 0.60
▸ L3MBTL1 Q9Y468 1/20 0.60
▸ FOLH1 Q04609 4/20 0.59
▸ CAPN1 P07384 2/20 0.51
▸ CNR1 P21554 1/20 0.51
▸ CA12 O43570 4/20 0.50
▸ CA1 P00915 4/20 0.50
▸ CA2 P00918 4/20 0.50
▸ CA9 Q16790 4/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30800274 1.00 TDP1 (0.61) TDP1HLCSMEN1ABL1LMNA
SCHEMBL5817718 0.98 HLCS (0.63) TDP1HLCSMEN1ABL1LMNA
SCHEMBL5821183 0.97 HLCS (0.64) TDP1HLCSMEN1ABL1LMNA
SCHEMBL515856 0.97 HLCS (0.64) TDP1HLCSMEN1ABL1LMNA
SCHEMBL2456107 0.97 HLCS (0.64) TDP1HLCSMEN1ABL1LMNA
SCHEMBL6159219 0.96 HLCS (0.60) TDP1HLCSMEN1ABL1LMNA
SCHEMBL30337427 0.95 HLCS (0.58) TDP1HLCSMEN1ABL1LMNA
SCHEMBL13034043 0.91 HLCS (0.59) TDP1HLCSMEN1ABL1LMNA
SCHEMBL15353872 0.90 TDP1 (0.64) TDP1HLCSMEN1ABL1LMNA
SCHEMBL739034 0.90 TDP1 (0.63) TDP1HLCSMEN1ABL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 159 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230391828-A1 REGULATORS OF CELL DIVISION TECHNISCHE UNIVERSITAT DRESDEN (DE) 2023-12-07 — — US claimed
CN-111624351-B Epitope identification method of bacterial antibody 江苏海洋大学 2023-11-24 — — CN claimed
EP-4225780-A2 REGULATORS OF CELL DIVISION Technische Universität Dresden (DE) 2023-08-16 — — EP claimed
EP-3996731-A1 PEPTIDES AND METHODS FOR TREATING DISEASES OP-T LLC (US) 2022-05-18 — — EP claimed
WO-2022074072-A2 REGULATORS OF CELL DIVISION Technische Universität Dresden (DE) 2022-04-14 — — WO claimed
EP-3981784-A1 REGULATORS OF CELL DIVISION Technische Universität Dresden (DE) 2022-04-13 — — EP claimed
EP-4744724-A2 PEPTIDES AND METHODS FOR TREATING DISEASES OP-T LLC (US) 2026-05-20 — — EP disclosed
EP-4729520-A1 CONFORMATIONALLY FIXED DIPROLINE MIMETICS AND THEIR USE Prosion GmbH (DE) 2026-04-22 — — EP disclosed
EP-4729523-A1 BICYCLIC DIPEPTIDE MIMETICS AND THEIR USE Prosion GmbH (DE) 2026-04-22 — — EP disclosed
EP-4726391-A1 NOVEL CITRULLINATED PEPTIDES THAT BIND TO ANTI-CITRULLINATED PROTEIN ANTIBODIES (ACPAS) AND THEIR USE IN THE DIAGNOSIS AND PREDICTION OF RHEUMATOID ARTHRITIS Vacara AB (SE) 2026-04-15 — — EP disclosed
US-12600710-B2 Beta-catenin and b-cell lymphoma 9 (BCL9) inhibitors Lee Moffitt Cancer Center and Research Institute, Inc. (US) 2026-04-14 — — US disclosed
US-20260085057-A1 SUBSTITUTED INDAZOLES USEFUL FOR TREATMENT AND PREVENTION OF ALLERGIC AND/OR INFLAMMATORY DISEASES IN ANIMALS Bayer Pharma AG (DE) 2026-03-26 — — US disclosed
EP-4712998-A1 DUAL-DOMAIN PEPTIDE FOR DEPLETING HMGB1 FROM THE CIRCULATION VIA LIVER HSPG SYSTEM The Medical College of Wisconsin (US) 2026-03-25 — — EP disclosed
CN-110305109-B Novel substituted indazoles, method for the production thereof, pharmaceutical preparations containing same, and use thereof for producing medicaments 拜耳医药股份有限公司 2022-04-08 — — CN disclosed
WO-2022067100-A2 PLK1 POLO BOX DOMAIN INHIBITOR AND METHOD OF TREATING CANCER THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2022-03-31 — — WO disclosed
EP-3959212-A1 4H-PYRROLO[3,2-C]PYRIDIN-4-ONE COMPOUNDS Bayer Aktiengesellschaft (DE) 2022-03-02 — — EP disclosed
EP-3959211-A1 4H-PYRROLO[3,2-C]PYRIDIN-4-ONE COMPOUNDS Bayer Aktiengesellschaft (DE) 2022-03-02 — — EP disclosed
EP-3958865-A1 4H-PYRROLO[3,2-C]PYRIDIN-4-ONE DERIVATIVES Bayer Aktiengesellschaft (DE) 2022-03-02 — — EP disclosed
CN-114127064-A 4H-pyrrolo [3,2-c ] pyridin-4-one compounds 拜耳股份有限公司 2022-03-01 — — CN disclosed
WO-2006121234-A1 BIOTIN-AMINO ACID CONJUGATE USEFUL AS A HYDROGELATOR AND HYDROGEL PREPARED THEREFROM POSTECH FOUNDATION (KR) 2006-11-16 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12600710-B2 Beta-catenin and b-cell lymphoma 9 (BCL9) inhibitors BCL9, BCL9L, BCL3 TDP1 4346/4885HLCS 887/4885MEN1 2873/4885
US-20260085057-A1 SUBSTITUTED INDAZOLES USEFUL FOR TREATMENT AND PREVENTION OF ALLERGIC AND/OR INFLAMMATORY DISEASES IN ANIMALS HRH4, BRCA1, HRH1 TDP1 3031/4885HLCS 1169/4885MEN1 2640/4885
US-20230391828-A1 REGULATORS OF CELL DIVISION PCNA, BOD1L1, MKI67 TDP1 1448/4885HLCS 1671/4885MEN1 1402/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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