Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HLCS | P50747 | 3/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.58 |
| ▸ | FOLH1 | Q04609 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | ABL1 | P00519 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | IDE | P14735 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.49 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5817718 | 0.98 | HLCS (0.63) | HLCSTDP1FOLH1MEN1ABL1 | |
| SCHEMBL515856 | 0.97 | HLCS (0.64) | HLCSTDP1FOLH1MEN1ABL1 | |
| SCHEMBL2456107 | 0.97 | HLCS (0.64) | HLCSTDP1FOLH1MEN1ABL1 | |
| SCHEMBL5821183 | 0.97 | HLCS (0.64) | HLCSTDP1FOLH1MEN1ABL1 | |
| SCHEMBL30337427 | 0.97 | HLCS (0.58) | HLCSTDP1FOLH1MEN1ABL1 | |
| SCHEMBL30800274 | 0.96 | TDP1 (0.61) | HLCSTDP1FOLH1MEN1ABL1 | |
| SCHEMBL5804916 | 0.96 | TDP1 (0.61) | HLCSTDP1FOLH1MEN1ABL1 | |
| SCHEMBL31065870 | 0.92 | HLCS (0.58) | HLCSTDP1FOLH1MEN1ABL1 | |
| SCHEMBL15353872 | 0.88 | TDP1 (0.64) | HLCSTDP1FOLH1MEN1ABL1 | |
| SCHEMBL739034 | 0.88 | TDP1 (0.63) | HLCSTDP1FOLH1MEN1ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5747352-A | Reagents and methods for the rapid and quantitative assay of pharmacological agents | BECKMAN INSTRUMENTS, INC. (US) | 1998-05-05 | — | — | US | claimed |
| EP-0710361-A1 | REAGENTS AND METHODS FOR THE RAPID AND QUANTITATIVE ASSAY OF PHARMACOLOGICAL AGENTS | BECKMAN INSTRUMENTS, INC. (US) | 1996-05-08 | — | — | EP | claimed |
| WO-1995032428-A1 | REAGENTS AND METHODS FOR THE RAPID AND QUANTITATIVE ASSAY OF PHARMACOLOGICAL AGENTS | BECKMAN INSTRUMENTS, INC. (US) | 1995-11-30 | — | — | WO | claimed |
| CN-114656791-B | Polymer-silica hybrid PDOT and methods of use thereof | 华盛顿大学 | 2024-02-09 | — | — | CN | disclosed |
| EP-0852005-B1 | COMPETITIVE IMMUNOASSAY DEVICE | BECKMAN COULTER INC (US) | 2005-02-09 | — | — | EP | disclosed |
| US-20030129191-A1 | Pretargeting methods and compounds | NEORX CORPORATION (US) | 2003-07-10 | — | — | US | disclosed |
| US-6416738-B1 | ADMINISTERING TO A RECIPIENT A FIRST CONJUGATE COMPRISING A TARGETING MOIETY AND A MEMBER OF A LIGAND/ANTI-LIGAND BINDING PAIR, THEREAFTER ADMINISTERING TO THE RECIPIENT A CLEARING AGENT, ADMINISTERING SECOND CONJUGATE | NEORX CORPORATION | 2002-07-09 | — | — | US | disclosed |
| US-6075010-A | Small molecular weight ligand-hexose containing clearing agents | NEORX CORPORATION (US) | 2000-06-13 | — | — | US | disclosed |
| EP-0315317-B2 | Bidentate conjugate and method of use thereof | BECKMAN INSTRUMENTS INC (US) | 2000-05-10 | — | — | EP | disclosed |
| EP-0852005-A4 | COMPETITIVE IMMUNOASSAY DEVICE | SMITHKLINE DIAGNOSTICS INC (US) | 1999-06-09 | — | — | EP | disclosed |
| EP-0743956-A4 | PRETARGETING METHODS AND COMPOUNDS | NEORX CORP (US) | 1999-03-24 | — | — | EP | disclosed |
| WO-1990009393-A1 | METHOD OF SEPARATING OLIGONUCLEOTIDES FROM A MIXTURE | WORCESTER FOUNDATION FOR EXPERIMENTAL BIOLOGY (US) | 1990-08-23 | — | — | WO | disclosed |
| EP-0165313-B1 | NUCLEIC ACID HYBRIDIZATION ASSAY | HRI RESEARCH, INC. (US) | 1989-11-15 | — | — | EP | disclosed |
| EP-0315317-A2 | Bidentate conjugate and method of use thereof | BECKMAN INSTRUMENTS, INC. (US) | 1989-05-10 | — | — | EP | disclosed |
| WO-1989003041-A2 | TRIDENTATE CONJUGATE AND METHOD OF USE THEREOF | BECKMAN INSTRUMENTS, INC. (US) | 1989-04-06 | — | — | WO | disclosed |
| EP-0310361-A2 | Tridentate conjugate and method of use thereof | BECKMAN INSTRUMENTS, INC. (US) | 1989-04-05 | — | — | EP | disclosed |
| US-4599303-A | PSORALEN DERIVATIVES | HRI ASSOCIATES, INC. (US) | 1986-07-08 | — | — | US | disclosed |
| EP-0165313-A4 | NUCLEIC ACID HYBRIDIZATION ASSAY. | HRI RES INC (US) | 1986-05-16 | — | — | EP | disclosed |
| EP-0165313-A1 | NUCLEIC ACID HYBRIDIZATION ASSAY. | HYDROCARBON RESEARCH INC (US) | 1985-12-27 | — | — | EP | disclosed |
| WO-1985002628-A1 | NUCLEIC ACID HYBRIDIZATION ASSAY | HRI RESEARCH, INC. (US) | 1985-06-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030129191-A1 | Pretargeting methods and compounds | BTD, HLCS, STRA6 | HLCS 2/4885TDP1 3339/4885FOLH1 124/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.