SCHEMBL5805189

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8103392	0.89	MAPT (0.68)	MAPTALDH1A1HTTSMN1; SMN2CA1
	SCHEMBL31429970	0.77	EGFR (0.74)	MAPTALDH1A1HTTCA1CA2
	SCHEMBL31429952	0.76	SMN1; SMN2 (0.61)	MAPTALDH1A1HTTSMN1; SMN2CA1
	SCHEMBL5802366	0.76	MAPT (0.57)	MAPTALDH1A1HTTSMN1; SMN2CA1
	SCHEMBL23269369	0.75	BCL2 (0.64)	RIPK1MEN1KMT2AATM
	SCHEMBL6294114	0.75	CA1 (0.56)	MAPTALDH1A1HTTSMN1; SMN2CA1
	SCHEMBL2687295	0.74	EGFR (0.78)	MAPTALDH1A1HTTCA1CA2
	SCHEMBL22796281	0.74	ESD (0.53)	MAPTALDH1A1HTTSMN1; SMN2RIPK1
	SCHEMBL5052866	0.74	MAPT (0.55)	MAPTALDH1A1HTTSMN1; SMN2PDE5A
	SCHEMBL5693269	0.74	MAPT (0.59)	MAPTALDH1A1HTTSMN1; SMN2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.