Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 11/20 | 0.64 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.61 |
| ▸ | TERT | O14746 | 3/20 | 0.61 |
| ▸ | BECN1 | Q14457 | 6/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.58 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18248229 | 0.90 | TERT (0.72) | RIPK1TERTMEN1KMT2AATM | |
| SCHEMBL18248225 | 0.85 | RIPK1 (0.63) | RIPK1TERTMEN1KMT2AMAOA | |
| SCHEMBL18248291 | 0.84 | TERT (0.68) | BCL2RIPK1TERTBECN1MEN1 | |
| SCHEMBL9370534 | 0.79 | LMNA (0.75) | RIPK1MAOB | |
| SCHEMBL23268895 | 0.77 | ALDH1A1 (0.64) | BCL2BECN1MEN1KMT2AATM | |
| SCHEMBL23268983 | 0.77 | BCL2 (0.61) | BCL2BECN1MEN1KMT2AATM | |
| SCHEMBL18255056 | 0.76 | RIPK1 (1.00) | RIPK1TERTCACNA1H | |
| SCHEMBL14541217 | 0.76 | CA1 (0.74) | BCL2BECN1MEN1KMT2AATM | |
| SCHEMBL14541214 | 0.76 | MEN1 (0.76) | BCL2BECN1MEN1KMT2ACACNA1H | |
| SCHEMBL18248369 | 0.76 | TERT (1.00) | TERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230203020-A1 | Small molecule inducers of autophagy | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2023-06-29 | — | — | US | disclosed |
| US-20230203020-A1 | Small molecule inducers of autophagy | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2023-06-29 | — | — | US | disclosed |
| US-11325898-B2 | Small molecule inducers of autophagy | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2022-05-10 | — | — | US | disclosed |
| US-20210115024-A1 | Small molecule inducers of autophagy | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2021-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11325898-B2 | Small molecule inducers of autophagy | BECN1, SQSTM1, MAP1LC3A | BCL2 11/4885RIPK1 114/4885TERT 2156/4885 |
| US-20210115024-A1 | Small molecule inducers of autophagy | BECN1, SQSTM1, MAP1LC3A | BCL2 11/4885RIPK1 114/4885TERT 2156/4885 |
| US-20230203020-A1 | Small molecule inducers of autophagy | BECN1, SQSTM1, MAP1LC3A | BCL2 11/4885RIPK1 114/4885TERT 2156/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.