SCHEMBL8103392

SCHEMBL8103392

CC1=NN(c2ccccc2)C(c2ccccc2)C1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.68
ALDH1A1 P00352 3/20 0.68
SMN1; SMN2 Q16637 2/20 0.68
HTT P42858 1/20 0.68
MEN1 O00255 6/20 0.54
KMT2A Q03164 6/20 0.54
ATM Q13315 4/20 0.54
RIPK1 Q13546 1/20 0.54
HSP90AA1 P07900 1/20 0.54
L3MBTL1 Q9Y468 3/20 0.53
KDM4E B2RXH2 2/20 0.53
GLA P06280 1/20 0.53
POLB P06746 1/20 0.53
MAPK1 P28482 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
PRKCZ Q05513 1/20 0.51
GAA P10253 2/20 0.50
MAOA P21397 2/20 0.50
MAOB P27338 2/20 0.50
PDE5A O76074 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5805189 0.89 MAPT (0.64) MAPTALDH1A1SMN1; SMN2HTTMEN1
SCHEMBL5693269 0.83 MAPT (0.59) MAPTALDH1A1SMN1; SMN2HTTMEN1
SCHEMBL22796281 0.80 ESD (0.53) MAPTALDH1A1SMN1; SMN2HTTKMT2A
SCHEMBL5052866 0.80 MAPT (0.55) MAPTALDH1A1SMN1; SMN2HTTMEN1
SCHEMBL13387492 0.79 MAPT (0.47) MAPTALDH1A1SMN1; SMN2HTTMEN1
SCHEMBL17012695 0.79 MAOB (0.64) MAPTALDH1A1SMN1; SMN2HTTKMT2A
SCHEMBL5802366 0.79 MAPT (0.57) MAPTALDH1A1SMN1; SMN2HTTMEN1
SCHEMBL11068412 0.78 MEN1 (0.54) MAPTALDH1A1SMN1; SMN2HTTMEN1
SCHEMBL31537146 0.78 MAPT (0.46) MAPTALDH1A1SMN1; SMN2HTTMEN1
SCHEMBL11208392 0.77 EGFR (0.74) MAPTALDH1A1HTTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119698496-A Electrochemical synthesis of pyrazolines and pyrazoles 拜耳公司 2025-03-25 CN disclosed
US-20200390100-A1 SUBSTITUTED N-HETEROCYCLYL- AND N-HETEROARYL-TETRAHYDROPYRIMIDINONES AND THE SALTS THEREOF, AND THE USE OF SAME AS HERBICIDAL ACTIVE SUBSTANCES BAYER AG (DE) 2020-12-17 US disclosed
EP-2592086-A1 TELOMERASE INHIBITORS AND A METHOD FOR THE PREPARATION THEREOF Gosudarstvennoe Uchebno-nauchnoe Uchrezhdenie Khimichesky Fakultet MGU Im. M.V. Lomonosova (RU) 2013-05-15 EP disclosed
EP-0357454-B1 Electrophotographic process XEROX CORP (US) 2000-12-27 EP disclosed
US-6156466-A Photoconductor for electrophotography FUJI ELECTRIC CO., LTD. (JP) 2000-12-05 US disclosed
US-5595851-A Conductive developer compositions with coated carrier particles XEROX CORPORATION (US) 1997-01-21 US disclosed
EP-0276147-B1 Toner and developer compositions with long chain alcohol waxes XEROX CORP (US) 1996-12-27 EP disclosed
EP-0278785-B1 Liquid developer compositions with high transfer efficiency XEROX CORP (US) 1996-05-29 EP disclosed
US-5322752-A Development process for abrasion resistant documents XEROX CORPORATION (US) 1994-06-21 US disclosed
US-5304450-A Processes for the preparation of toner compositions XEROX CORPORATION (US) 1994-04-19 US disclosed
US-4073965-A SULFONAMIDO PHTHALOCYANINE TONER RESINS XEROX CORPORATION (US) 1978-02-14 US disclosed
US-4066563-A COPPER-TETRA-4-(OCTADECYLSULFONOMIDO) PHTHALOCYANINE ELECTROPHOTOGRAPHIC CARRIER XEROX CORPORATION (US) 1978-01-03 US disclosed
US-4063946-A Electrophotographic color reproduction process employing photoconductive material with dual light fatigue properties RANK XEROX LTD. (EN) 1977-12-20 US disclosed
US-4058397-A ELECTROGRAPHY, DISAZO DYE, COPPER TETRA-4-(OCTADECYL SULFONAMIDO) PHTHALOCYANINE XEROX CORPORATION (US) 1977-11-15 US disclosed
US-4057426-A ELECTROSTATIC, 2,9-DIMETHYL-QUINACRIDONE, COPPER TETRA-4-(OCTADECYLSULFONAMIDO) PHTHALOCYANINE XEROX CORPORATION (US) 1977-11-08 US disclosed
US-4043929-A Electrostatographic carrier composition XEROX CORPORATION (US) 1977-08-23 US disclosed
US-4019842-A Apparatus for forming magnetite electrostatographic carriers XEROX CORPORATION (US) 1977-04-26 US disclosed
US-3989860-A Repair technique for photoreceptors XEROX CORPORATION (US) 1976-11-02 US disclosed
US-3963486-A Electrophotographic imaging process employing epoxy-ester containing liquid developer RANK XEROX LTD. (EN) 1976-06-15 US disclosed
US-3955977-A GRAPHIC DISPLAYS XEROX CORPORATION (US) 1976-05-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200390100-A1 SUBSTITUTED N-HETEROCYCLYL- AND N-HETEROARYL-TETRAHYDROPYRIMIDINONES AND THE SALTS THEREOF, AND THE USE OF SAME AS HERBICIDAL ACTIVE SUBSTANCES DDT, NOTUM, AGPS MAPT 3730/4885ALDH1A1 201/4885SMN1; SMN2 4626/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.