Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.77 |
| ▸ | LMNA | P02545 | 4/20 | 0.77 |
| ▸ | MAPT | P10636 | 5/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | GFER | P55789 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.54 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1101900 | 0.84 | LMNA (0.77) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL5805038 | 0.78 | POLB (0.64) | ALDH1A1LMNAMAPTKMT2ANPSR1 | |
| SCHEMBL5804877 | 0.78 | NPSR1 (0.65) | ALDH1A1LMNAMAPTKMT2ANPSR1 | |
| SCHEMBL19090711 | 0.75 | LMNA (0.75) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL19079791 | 0.75 | LMNA (0.70) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL19079790 | 0.75 | LMNA (0.74) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL5807546 | 0.72 | NPSR1 (0.70) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL5804328 | 0.70 | ALDH1A1 (0.59) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL14478929 | 0.69 | MAPK1 (0.62) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL3911841 | 0.68 | TP53 (0.68) | ALDH1A1LMNAMAPTKMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006093518-A2 | THIENYL COMPOUNDS FOR TREATING VIRUS-RELATED CONDITIONS | APATH, LLC (US) | 2006-09-08 | — | — | WO | disclosed |