Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 5/20 | 0.46 |
| ▸ | SCD | O00767 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMO | Q99835 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | RBP4 | P02753 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.40 |
| ▸ | CCR3 | P51677 | 1/20 | 0.40 |
| ▸ | OGA | O60502 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5810600 | 0.87 | OGA (0.40) | RORCSCDKMT2AMEN1MAPT | |
| SCHEMBL5809214 | 0.85 | HPGDS (0.52) | SCDKMT2A | |
| SCHEMBL1742861 | 0.83 | HPGD (0.45) | RORCHPGDNPSR1NPC1RAB9A | |
| SCHEMBL5809031 | 0.83 | SCD (0.48) | RORCSCDHPGDNPSR1NPC1 | |
| SCHEMBL5808105 | 0.81 | SCD (0.47) | SCD | |
| SCHEMBL5808456 | 0.78 | RORC (0.46) | RORCSCDHPGDNPSR1RBP4 | |
| SCHEMBL3677226 | 0.76 | SCD (0.71) | SCDKMT2ALMNAHTTMEN1 | |
| SCHEMBL4252698 | 0.75 | TNF (0.48) | HPGDNPSR1KMT2ARBP4MEN1 | |
| SCHEMBL5809607 | 0.74 | SCD (0.64) | SCD | |
| SCHEMBL5809211 | 0.74 | SCD (0.48) | SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006125181-A2 | PIPERIDINE DERIVATIVES AND THEIR USE AS STEAROYL-COA DESATURASE MODULATORS | XENON PHARMACEUTICALS INC. (CA) | 2006-11-23 | — | — | WO | disclosed |