Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 1/20 | 0.40 |
| ▸ | SCD | O00767 | 3/20 | 0.40 |
| ▸ | SFRP1 | Q8N474 | 2/20 | 0.39 |
| ▸ | RORC | P51449 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.37 |
| ▸ | MPL | P40238 | 1/20 | 0.37 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.37 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5805495 | 0.87 | RORC (0.46) | OGASCDSFRP1RORCSMN1; SMN2 | |
| SCHEMBL5806175 | 0.82 | SCD (0.44) | SCD | |
| SCHEMBL5805986 | 0.79 | KDM4E (0.44) | SMN1; SMN2MAPTKDM4EMEN1KMT2A | |
| SCHEMBL5808458 | 0.79 | RBP4 (0.39) | SCDRORC | |
| SCHEMBL2760778 | 0.78 | SCD (0.55) | SCDSMN1; SMN2KDM4EMEN1CYP1A2 | |
| SCHEMBL5810428 | 0.74 | SCD (0.58) | SCD | |
| SCHEMBL5809214 | 0.73 | HPGDS (0.52) | SCDKMT2A | |
| SCHEMBL5809576 | 0.73 | SCD (0.52) | SCD | |
| SCHEMBL5805823 | 0.72 | PARP1 (0.45) | SCD | |
| SCHEMBL5820146 | 0.72 | DCTPP1 (0.59) | SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006125181-A2 | PIPERIDINE DERIVATIVES AND THEIR USE AS STEAROYL-COA DESATURASE MODULATORS | XENON PHARMACEUTICALS INC. (CA) | 2006-11-23 | — | — | WO | disclosed |