Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 18/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5110002 | 0.79 | KIF11 (0.42) | ALDH1A1MEN1KMT2AKIF11 | |
| SCHEMBL4373915 | 0.76 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2AKIF11GAA | |
| SCHEMBL4507515 | 0.71 | KIF11 (0.55) | ALDH1A1MEN1KMT2AKIF11 | |
| SCHEMBL5110435 | 0.69 | LMNA (0.38) | ALDH1A1MEN1KMT2AKIF11GAA | |
| SCHEMBL4523593 | 0.67 | KIF11 (0.57) | ALDH1A1MEN1KMT2AKIF11 | |
| SCHEMBL4375027 | 0.65 | LMNA (0.43) | ALDH1A1MEN1KMT2AKIF11HPGD | |
| SCHEMBL4514513 | 0.65 | KIF11 (0.54) | ALDH1A1MEN1KMT2AKIF11 | |
| SCHEMBL13865434 | 0.65 | KIF11 (0.54) | ALDH1A1MEN1KMT2AKIF11 | |
| SCHEMBL4516475 | 0.62 | KIF11 (0.53) | ALDH1A1MEN1KMT2AKIF11 | |
| SCHEMBL5806031 | 0.62 | KIF11 (0.53) | ALDH1A1MEN1KMT2AKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513820-A4 | COMPOUNDS, COMPOSITIONS, AND METHODS | CYTOKINETICS INC (US) | 2006-09-13 | — | — | EP | disclosed |
| EP-1513820-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2005-03-16 | — | — | EP | disclosed |
| WO-2003103575-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2003-12-18 | — | — | WO | disclosed |