Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.70 |
| ▸ | GAA | P10253 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.67 |
| ▸ | HPGD | P15428 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5807226 | 0.90 | LMNA (0.71) | LMNAGAAALDH1A1HPGDMAPT | |
| SCHEMBL5804336 | 0.87 | POLB (0.74) | LMNAGAAALDH1A1HPGDMAPT | |
| SCHEMBL5804285 | 0.86 | MAPT (0.72) | LMNAGAAALDH1A1HPGDMAPT | |
| SCHEMBL8289363 | 0.85 | POLB (0.71) | LMNAGAAALDH1A1HPGDMAPT | |
| SCHEMBL3931523 | 0.83 | PTPN1 (0.78) | LMNAGAAALDH1A1HPGDMAPT | |
| SCHEMBL5804332 | 0.78 | POLB (0.74) | LMNAGAAALDH1A1HPGDMAPT | |
| SCHEMBL14478927 | 0.78 | TP53 (0.65) | LMNAGAAALDH1A1HPGDMAPT | |
| SCHEMBL689196 | 0.77 | PRKCZ (0.78) | GAAALDH1A1HPGDMAPTKMT2A | |
| SCHEMBL23579845 | 0.77 | POLB (0.72) | LMNAGAAALDH1A1HPGDMAPT | |
| SCHEMBL5919026 | 0.76 | PRKCZ (0.62) | LMNAGAAALDH1A1MAPTPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006093518-A2 | THIENYL COMPOUNDS FOR TREATING VIRUS-RELATED CONDITIONS | APATH, LLC (US) | 2006-09-08 | — | — | WO | disclosed |