Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.64 |
| ▸ | HTT | P42858 | 4/20 | 0.64 |
| ▸ | CRHBP | P24387 | 1/20 | 0.64 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 5/20 | 0.59 |
| ▸ | HPGD | P15428 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5804278 | 0.91 | MAPT (0.73) | MAPTALDH1A1HTTCRHBPCRHR2 | |
| SCHEMBL13837645 | 0.88 | MAPT (0.76) | MAPTALDH1A1HTTCRHBPCRHR2 | |
| SCHEMBL5807228 | 0.86 | LMNA (0.70) | MAPTALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL8290370 | 0.83 | MAPT (0.68) | MAPTALDH1A1HTTCRHBPCRHR2 | |
| SCHEMBL5804336 | 0.82 | POLB (0.74) | MAPTALDH1A1HTTLMNAHPGD | |
| SCHEMBL8288763 | 0.80 | MAPT (0.64) | MAPTALDH1A1HTTCRHBPCRHR2 | |
| SCHEMBL8288714 | 0.79 | PRKCZ (0.81) | MAPTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL5807226 | 0.76 | LMNA (0.71) | MAPTALDH1A1HTTLMNAHPGD | |
| SCHEMBL5804332 | 0.73 | POLB (0.74) | MAPTALDH1A1HTTLMNAHPGD | |
| SCHEMBL14478927 | 0.73 | TP53 (0.65) | MAPTALDH1A1HTTLMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006093518-A2 | THIENYL COMPOUNDS FOR TREATING VIRUS-RELATED CONDITIONS | APATH, LLC (US) | 2006-09-08 | — | — | WO | disclosed |