Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5807441 | 1.00 | L3MBTL1 (0.56) | L3MBTL1MAPTSMN1; SMN2GAANPC1 | |
| SCHEMBL5806577 | 0.83 | L3MBTL1 (0.51) | L3MBTL1MAPTSMN1; SMN2GAANPC1 | |
| SCHEMBL2313267 | 0.83 | ALDH1A1 (0.50) | L3MBTL1MAPTSMN1; SMN2GAANPC1 | |
| SCHEMBL5806575 | 0.83 | L3MBTL1 (0.51) | L3MBTL1MAPTSMN1; SMN2GAANPC1 | |
| SCHEMBL28241514 | 0.83 | HPGD (0.56) | L3MBTL1MAPTSMN1; SMN2GAANPC1 | |
| SCHEMBL1665548 | 0.76 | GRIN2D (0.61) | MAPTSMN1; SMN2GAANPC1RAB9A | |
| SCHEMBL29538287 | 0.76 | ALDH1A1 (0.55) | L3MBTL1MAPTSMN1; SMN2GAAHPGD | |
| SCHEMBL31182413 | 0.76 | GRIN2D (0.61) | MAPTSMN1; SMN2GAANPC1RAB9A | |
| SCHEMBL15678969 | 0.76 | POLB (0.45) | L3MBTL1MAPTSMN1; SMN2GAANPC1 | |
| SCHEMBL908602 | 0.76 | ALDH1A1 (0.55) | L3MBTL1MAPTSMN1; SMN2GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006093518-A2 | THIENYL COMPOUNDS FOR TREATING VIRUS-RELATED CONDITIONS | APATH, LLC (US) | 2006-09-08 | — | — | WO | disclosed |