Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | DRD1 | P21728 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | SRC | P12931 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29538287 | 1.00 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2HPGDHTTDRD1 | |
| SCHEMBL10451671 | 0.84 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2HPGDHTTDRD1 | |
| SCHEMBL5083611 | 0.84 | DRD1 (0.47) | ALDH1A1SMN1; SMN2HPGDHTTDRD1 | |
| SCHEMBL2934551 | 0.82 | LMNA (0.52) | ALDH1A1SMN1; SMN2HPGDHTTDRD1 | |
| SCHEMBL27034832 | 0.82 | DRD1 (0.50) | ALDH1A1SMN1; SMN2HPGDHTTDRD1 | |
| SCHEMBL30768062 | 0.82 | DRD1 (0.50) | ALDH1A1SMN1; SMN2HPGDHTTDRD1 | |
| SCHEMBL15270748 | 0.82 | DRD1 (0.43) | ALDH1A1SMN1; SMN2HPGDHTTDRD1 | |
| SCHEMBL4115873 | 0.81 | DRD1 (0.45) | ALDH1A1SMN1; SMN2HPGDHTTDRD1 | |
| SCHEMBL8962725 | 0.81 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2HPGDHTTDRD1 | |
| SCHEMBL6898729 | 0.81 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2HPGDHTTDRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 467 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116867782-A | Pyrazole amide derivative | 豪夫迈·罗氏有限公司 | 2023-10-10 | — | — | CN | claimed |
| CN-103304408-B | The preparation of roflumilast intermediate 3-ring the third methoxyl group-4-difluoro-methoxy-benzoic acid | 威海迪素制药有限公司 | 2016-10-05 | — | — | CN | claimed |
| US-20060084176-A1 | Detection of uronium salts | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2006-04-20 | — | — | US | claimed |
| US-20040132807-A1 | Aurones as telomerase inhibitors | PHARMACIA ITALIA SPA (IT) | 2004-07-08 | — | — | US | claimed |
| EP-1381359-A1 | AURONES AS TELOMERASE INHIBITORS | Pharmacia Italia S.p.A. (IT) | 2004-01-21 | — | — | EP | claimed |
| WO-2002083123-A1 | AURONES AS TELOMERASE INHIBITORS | PHARMACIA ITALIA SPA (IT) | 2002-10-24 | — | — | WO | claimed |
| EP-0639559-B1 | Preparation of 1,2-diacyl-2-(t-alkyl)hydrazines | ROHM & HAAS (US) | 1997-10-15 | — | — | EP | claimed |
| JP-58008035-A | — | — | None | — | — | JP | disclosed |
| JP-2059557-A | — | — | None | — | — | JP | disclosed |
| EP-4713320-A2 | BCAT2 INHIBITORS | Agios Pharmaceuticals, Inc. (US) | 2026-03-25 | — | — | EP | disclosed |
| US-12577242-B2 | Pyrrolopyridine and imidazopyridine antiviral compounds | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2026-03-17 | — | — | US | disclosed |
| US-20250326744-A1 | PIPERAZINE DERIVATIVE OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION | FUJIFILM CORPORATION (JP) | 2025-10-23 | — | — | US | disclosed |
| US-20250304594-A1 | METHYL (R)-2-(FLUOROMETHYL)-5-OXO-4-PHENYL-4,5,6,7-TETRAHYDRO-1H-CYCLOPENTA[B]PYRIDINE-3-CARBOXYLATE AND METHYL (R)-2-(FLUOROMETHYL)-5-OXO-4-PHENYL-1,4,5,7-TETRAHYDROFURO[3,4-B]PYRIDINE-3-CARBOXYLATE AS Cav1,2 ACTIVATORS | NOVARTIS AG (CH) | 2025-10-02 | — | — | US | disclosed |
| US-4438275-A | 2,2-DIFLUORO-BENZODIOXOLES | BAYER AKTIENGESELLSCHAFT (DE) | 1984-03-20 | — | — | US | disclosed |
| JP-S588035-A | DIFLUOROMETHOXYPHENYL KETONE DERIVATIVE AND ITS PREPARATION | NISSAN CHEM IND LTD | 1983-01-18 | — | — | JP | disclosed |
| US-4316989-A | Process for preparing difluoromethoxy derivatives of aromatic aldehydes | FIALKOV JURY A | 1982-02-23 | — | — | US | disclosed |
| US-4310540-A | PYRETHROID-LIKE COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DE) | 1982-01-12 | — | — | US | disclosed |
| EP-0041131-A2 | Preparation of fluoro-substituted benzodioxoles and benzodioxanes | BAYER AG (DE) | 1981-12-09 | — | — | EP | disclosed |
| US-4219653-A | HYPOTENSIVE AGENTS OF LOW TOXICITY | DUBUR GUNAR Y (SU) | 1980-08-26 | — | — | US | disclosed |
| EP-0006978-A2 | Benzyl esters with fluorinated ether and/or thioether groups, their preparations and their use as insecticides; intermediate products and their preparations | BAYER AG (DE) | 1980-01-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250304594-A1 | METHYL (R)-2-(FLUOROMETHYL)-5-OXO-4-PHENYL-4,5,6,7-TETRAHYDRO-1H-CYCLOPENTA[B]PYRIDINE-3-CARBOXYLATE AND METHYL (R)-2-(FLUOROMETHYL)-5-OXO-4-PHENYL-1,4,5,7-TETRAHYDROFURO[3,4-B]PYRIDINE-3-CARBOXYLATE AS Cav1,2 ACTIVATORS | CACNA1D, CACNA1B, CACNA1S | ALDH1A1 2045/4885SMN1; SMN2 353/4885HPGD 3885/4885 |
| US-12577242-B2 | Pyrrolopyridine and imidazopyridine antiviral compounds | SARS1, TPMT, ZC3HAV1 | ALDH1A1 3438/4885SMN1; SMN2 770/4885HPGD 4049/4885 |
| US-20040132807-A1 | Aurones as telomerase inhibitors | TERT, TERF2, TERF2IP | ALDH1A1 1344/4885SMN1; SMN2 2455/4885HPGD 3095/4885 |
| US-20250326744-A1 | PIPERAZINE DERIVATIVE OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION | ABCB11, ABCC1, SLC11A2 | ALDH1A1 774/4885SMN1; SMN2 2951/4885HPGD 1533/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.